Literature DB >> 28289647

Central Pontine Myelinolysis Induced by Alcohol Withdrawal: A Case Report.

Jae Ho Kim1, Sae Hyun Kim1, Ho Joong Jeong1, Young Joo Sim1, Dong Kyu Kim1, Ghi Chan Kim1.   

Abstract

Central pontine myelinolysis (CPM) is a demyelinating disorder characterized by the loss of myelin in the center of the basis pons, and is mainly caused by the rapid correction of hyponatremia. We report the case of a young woman who presented with gait disturbance and alcohol withdrawal, and who was eventually diagnosed with CPM. Generally, the cause and pathogenesis of CPM in chronic alcoholics remain unclear. In this cases, the CPM may be unrelated to hyponatremia or its correction. However, it is possible that the osmotic pressure changes due to refeeding syndrome after alcohol withdrawal was the likely cause in this case. This case illustrates the need for avoiding hasty, and possibly incomplete diagnoses, and performing more intensive test procedures to ensure a correct diagnosis.

Entities:  

Keywords:  Alcohol withdrawal; Central pontine myelinolysis

Year:  2017        PMID: 28289647      PMCID: PMC5344816          DOI: 10.5535/arm.2017.41.1.148

Source DB:  PubMed          Journal:  Ann Rehabil Med        ISSN: 2234-0645


  10 in total

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