| Literature DB >> 28287272 |
Ying Peng1,2, Yuqing Jian1, Ali Zulfiqar2, Bin Li1, Kaiqiang Zhang1,2, Fei Long1,2, Caiyun Peng1, Xiong Cai1, Ikhlas A Khan1,2, Wei Wang1.
Abstract
Two new sesquiterpene lactone glycosides, namely melitensin 15-O-β-D-glucoside (1) and 11β,13-dihydrosalonitenolide 15-O-β-D-glucoside (2), along with eight known compounds (3-10) were isolated from the aerial part of Cnicus benedictus L. Their structures were elucidated from analyses of extensive spectroscopic data. Compounds 1-6 all possessed an α-methyl-γ-lactone moiety. Moreover, compound 5 exhibited moderate activity against the growth of Aspergillus fumigatus, with IC50 values of 17.67 μg mL-1.Entities:
Keywords: Asteraceae; Cnicus benedictus; antimicrobial; sesquiterpene lactone glycosides
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Year: 2017 PMID： 28287272 DOI： 10.1080/14786419.2017.1295239
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861