Valeriy Shubinets1, Justin P Fox1, Michael G Tecce1, Michael N Mirzabeigi1, Michael A Lanni1, Rachel R Kelz2, Kristoffel R Dumon3, Stephen J Kovach1, John P Fischer4. 1. Division of Plastic Surgery, Department of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA. 2. Division of Endocrine and Oncologic Surgery, Department of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA. 3. Division of Gastrointestinal Surgery, Department of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA. 4. Division of Plastic Surgery, Department of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA. Electronic address: John.Fischer2@uphs.upenn.edu.
Abstract
BACKGROUND: Panniculectomy (PAN) is often performed concurrently with ventral hernia repair (VHR) in the obese patient. However, the effectiveness and safety profile of this common practice are not fully established in part because of paucity of comparative effectiveness studies. In this study, a comparative analysis of early complications, long-term hernia recurrence, and healthcare expenditures between VHR-PAN and VHR-only patients is presented. METHODS: From the Healthcare Cost and Utilization Project database, obese patients who underwent VHR with and without concurrent PAN were identified. Multivariate cox proportional-hazards regression modeling was performed to compare outcomes between the two groups. RESULTS: The final cohort included 1013 VHR-PAN and 18,328 VHR-only patients. The VHR-PAN patients experienced a longer adjusted length of hospital stay (6.8 days vs. 5.2 days; p < 0.001), a higher rate of in-hospital adverse events (29.3% vs. 20.7%; AOR = 2.34 [2.01-2.74]), and a higher rate of 30-day readmissions (13.6% vs. 8.1%; AOR = 2.04 [1.69-2.48]). However, the 2-year rate of hernia recurrence was lower in the VHR-PAN group (7.9% vs. 11.3%; AOR = 0.65 [0.51-0.82]). Both groups generated considerable hospital charges ($104,805 VHR-PAN vs. $72,206 VHR-only, p < 0.001). CONCLUSION: Performing a concurrent PAN in the obese hernia patient is associated with a higher rate of early complications and greater healthcare expenditures, but overall a substantially lower incidence of 2-year hernia recurrence. The literature review presented here also highlights a substantial need for further comparative effectiveness studies to create the needed framework for evidence-based guidelines.
BACKGROUND: Panniculectomy (PAN) is often performed concurrently with ventral hernia repair (VHR) in the obesepatient. However, the effectiveness and safety profile of this common practice are not fully established in part because of paucity of comparative effectiveness studies. In this study, a comparative analysis of early complications, long-term hernia recurrence, and healthcare expenditures between VHR-PAN and VHR-only patients is presented. METHODS: From the Healthcare Cost and Utilization Project database, obesepatients who underwent VHR with and without concurrent PAN were identified. Multivariate cox proportional-hazards regression modeling was performed to compare outcomes between the two groups. RESULTS: The final cohort included 1013 VHR-PAN and 18,328 VHR-only patients. The VHR-PAN patients experienced a longer adjusted length of hospital stay (6.8 days vs. 5.2 days; p < 0.001), a higher rate of in-hospital adverse events (29.3% vs. 20.7%; AOR = 2.34 [2.01-2.74]), and a higher rate of 30-day readmissions (13.6% vs. 8.1%; AOR = 2.04 [1.69-2.48]). However, the 2-year rate of hernia recurrence was lower in the VHR-PAN group (7.9% vs. 11.3%; AOR = 0.65 [0.51-0.82]). Both groups generated considerable hospital charges ($104,805 VHR-PAN vs. $72,206 VHR-only, p < 0.001). CONCLUSION: Performing a concurrent PAN in the obese herniapatient is associated with a higher rate of early complications and greater healthcare expenditures, but overall a substantially lower incidence of 2-year hernia recurrence. The literature review presented here also highlights a substantial need for further comparative effectiveness studies to create the needed framework for evidence-based guidelines.
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