Eimear Linehan1, Marian Brennan2, Sadhbh O'Rourke3, Suzie Coughlan4, Lisa Clooney5, David LeBlanc6, Joanna Griffin7, Maeve Eogan8, Richard J Drew6,9. 1. a Royal College of Surgeons in Ireland , Dublin , Ireland. 2. b Department of Infection Prevention and Control , Rotunda Hospital , Dublin , Ireland. 3. c Department of Clinical Microbiology , Temple Street Children's University Hospital , Dublin , Ireland. 4. d National Virus Reference Laboratory, University College Dublin , Dublin , Ireland. 5. e Department of Pharmacy , Rotunda Hospital , Dublin , Ireland. 6. f Department of Clinical Microbiology , Rotunda Hospital , Dublin , Ireland. 7. g Department of Research , Rotunda Hospital , Dublin , Ireland. 8. h Department of Obstetrics , Rotunda Hospital , Dublin , Ireland. 9. i Department of Clinical Microbiology , Royal College of Surgeons in Ireland , Dublin , Ireland.
Abstract
OBJECTIVE: The aim of this project was to assess the implementation of a quality improvement project regarding the introduction of on-site influenza PCR testing in a stand-alone obstetric hospital. METHODS: As part of a quality improvement project on the management of influenza in obstetric patients, the Xpert Flu assay (Cepheid Inc., Sunnyvale, CA) was introduced on-site and it replaced the previous method of PCR testing which was off-site. The main outcome measures were duration of antimicrobials, rate of admission and administration of oseltamavir in the emergency department. RESULTS: Twenty-eight patients were included in the pre-intervention period and 45 patients were included in the post-intervention period. Following the introduction of the test, there was a statistically significant reduction seen in commencement of antimicrobials (76% pre- and 33% post-intervention), and also rate of admission (88% pre- and 45% post-intervention) while there was a statistically significant improvement in the commencement of oseltamavir in the emergency department (72% pre-and 95% post-intervention) (p < .01 for all outcomes). CONCLUSION: Introduction of on-site rapid influenza PCR testing can lead to a significant improvement in patient management and should be considered for introduction to other sites.
OBJECTIVE: The aim of this project was to assess the implementation of a quality improvement project regarding the introduction of on-site influenza PCR testing in a stand-alone obstetric hospital. METHODS: As part of a quality improvement project on the management of influenza in obstetric patients, the Xpert Flu assay (Cepheid Inc., Sunnyvale, CA) was introduced on-site and it replaced the previous method of PCR testing which was off-site. The main outcome measures were duration of antimicrobials, rate of admission and administration of oseltamavir in the emergency department. RESULTS: Twenty-eight patients were included in the pre-intervention period and 45 patients were included in the post-intervention period. Following the introduction of the test, there was a statistically significant reduction seen in commencement of antimicrobials (76% pre- and 33% post-intervention), and also rate of admission (88% pre- and 45% post-intervention) while there was a statistically significant improvement in the commencement of oseltamavir in the emergency department (72% pre-and 95% post-intervention) (p < .01 for all outcomes). CONCLUSION: Introduction of on-site rapid influenza PCR testing can lead to a significant improvement in patient management and should be considered for introduction to other sites.
Authors: Nasir Wabe; Ling Li; Maria R Dahm; Robert Lindeman; Ruth Yimsung; Kate Clezy; Judith Thomas; Wayne Varndell; Johanna Westbrook; Andrew Georgiou Journal: BMJ Open Date: 2019-08-08 Impact factor: 2.692
Authors: Nasir Wabe; Ling Li; Robert Lindeman; Ruth Yimsung; Maria R Dahm; Kate Clezy; Susan McLennan; Johanna Westbrook; Andrew Georgiou Journal: Med J Aust Date: 2019-03-05 Impact factor: 7.738
Authors: Laura M Vos; Jesper M Weehuizen; Andy I M Hoepelman; Karin H A H Kaasjager; Annelies Riezebos-Brilman; Jan Jelrik Oosterheert Journal: J Clin Virol Date: 2019-04-07 Impact factor: 3.168
Authors: Laura M Vos; Andrea H L Bruning; Johannes B Reitsma; Rob Schuurman; Annelies Riezebos-Brilman; Andy I M Hoepelman; Jan Jelrik Oosterheert Journal: Clin Infect Dis Date: 2019-09-13 Impact factor: 9.079