Ming-Li Liou1, Kuan-Hsueh Chen2, Hui-Ling Yeh1, Chun-Yi Lai3, Chang-Hua Chen4. 1. Department of Medical Laboratory Science and Biotechnology, Yuanpei University, Hsin-Chu City, Taiwan. 2. Department of Computer Science and Information Engineering, Providence University, Taichung City, Taiwan. 3. Department of Medicine, Nantou Christian Hospital, Nantou City, Taiwan. 4. Division of Infectious Diseases, Department of Internal Medicine, Changhua Christian Hospital, Changhua City, Taiwan; Center for Infectious Diseases Research, Changhua Christian Hospital, Changhua City, Taiwan; Department of Nursing, College of Medicine & Nursing, Hung Kuang University, Taichung City, Taiwan. Electronic address: chenchanghuachad@gmail.com.
Abstract
BACKGROUND: Acinetobacter baumannii and Staphylococcus aureus have persisted as 2 major pathogens worldwide. AIM: We designed a prevalence study to investigate the prevalence of nasal carriage of S aureus and A baumannii in long-term-care facilities (LCTFs) and their collaborative community hospitals. In addition, we aimed to clarify persistent or nonpersistent carriage of the 2 organisms among residents of LTCFs. METHODS: We performed a prevalence study concerning nasal carriers of A baumannii and S aureus in 3 LTCFs and 1 collaborative community hospital. RESULTS: Seventy subjects were enrolled and clustered into 3 groups: the elderly sick group (n = 24), the elderly healthy group (n = 33), and the healthy health care worker group (n = 13). Nasal samples were collected, and the nuc and mecA genes of S aureus and the blaOXA gene of A baumannii were analyzed by polymerase chain reaction. Among the 3 groups, the rate of nasal carriage of S aureus was approximately 0%-15%. However, the rate for A baumannii was approximately 54%-92%. Notably, the persistent carrier rate of A baumannii in the elderly sick group was 83.3% (20 out of 24) despite a 12.5% (3 out of 24) rate of carbapenem-resistant A baumannii. CONCLUSIONS: We emphasized that the persistent nasal carriage of A baumannii in LTCFs could be another portal of exit to cause A baumannii infection in Taiwan.
BACKGROUND: Acinetobacter baumannii and Staphylococcus aureus have persisted as 2 major pathogens worldwide. AIM: We designed a prevalence study to investigate the prevalence of nasal carriage of S aureus and A baumannii in long-term-care facilities (LCTFs) and their collaborative community hospitals. In addition, we aimed to clarify persistent or nonpersistent carriage of the 2 organisms among residents of LTCFs. METHODS: We performed a prevalence study concerning nasal carriers of A baumannii and S aureus in 3 LTCFs and 1 collaborative community hospital. RESULTS: Seventy subjects were enrolled and clustered into 3 groups: the elderly sick group (n = 24), the elderly healthy group (n = 33), and the healthy health care worker group (n = 13). Nasal samples were collected, and the nuc and mecA genes of S aureus and the blaOXA gene of A baumannii were analyzed by polymerase chain reaction. Among the 3 groups, the rate of nasal carriage of S aureus was approximately 0%-15%. However, the rate for A baumannii was approximately 54%-92%. Notably, the persistent carrier rate of A baumannii in the elderly sick group was 83.3% (20 out of 24) despite a 12.5% (3 out of 24) rate of carbapenem-resistant A baumannii. CONCLUSIONS: We emphasized that the persistent nasal carriage of A baumannii in LTCFs could be another portal of exit to cause A baumannii infection in Taiwan.
Authors: Peter Klotz; Paul G Higgins; Andreas R Schaubmar; Klaus Failing; Ursula Leidner; Harald Seifert; Sandra Scheufen; Torsten Semmler; Christa Ewers Journal: Front Microbiol Date: 2019-02-22 Impact factor: 5.640
Authors: Claudia Peters; Madeleine Dulon; Albert Nienhaus; Anja Schablon Journal: Int J Environ Res Public Health Date: 2019-06-04 Impact factor: 3.390