Laurent Maïmoun1, Patrick Lefebvre2, Audrey Jaussent3, Clémence Fouillade4, Denis Mariano-Goulart5, David Nocca4. 1. Service de Médecine Nucléaire, Hôpital Lapeyronie, Centre Hospitalier Régional Universitaire (CHRU) Montpellier et Université Montpellier (UM), Montpellier, France; Physiologie et Médecine Expérimentale du Cœur et des Muscles (PhyMedExp), U1046 INSERM, UMR9214 CNRS, University of Montpellier, Montpellier, France. Electronic address: l-maimoun@chu-montpellier.fr. 2. Departement d'Endocrinology, Diabetes, Nutrition, Hôpital Lapeyronie, CHRU, Montpellier, France. 3. Unité de recherche clinique, biostatistiques et épidémiologie, Département de l'Information Médicale, CHRU, Montpellier, France. 4. Service de Chirurgie Digestive A, Hôpital Saint Eloi, CHRU, Montpellier, France. 5. Service de Médecine Nucléaire, Hôpital Lapeyronie, Centre Hospitalier Régional Universitaire (CHRU) Montpellier et Université Montpellier (UM), Montpellier, France; Physiologie et Médecine Expérimentale du Cœur et des Muscles (PhyMedExp), U1046 INSERM, UMR9214 CNRS, University of Montpellier, Montpellier, France.
Abstract
BACKGROUND: Sleeve gastrectomy (SG) induces acute weight loss, but its impact on the very early postoperative changes in body composition (BC) is less clear. OBJECTIVES: This longitudinal study examined the BC changes in the first month after SG according to gender and anatomic site. METHODS: BC (lean tissue mass [LTM] and fat mass [FM]) were determined by dual-energy x-ray absorptiometry in 41 obese patients (33 women, 80.5%) just before SG and 1 month later. SETTING: University hospital of Montpellier, France. RESULTS: One month after SG, mean weight loss was -9.8±2.6 kg, with a significant decrease in LTM and FM (kg) ranging from -7.3% to 9.5%, depending on site. FM (kg) loss in men exceeded that in women at whole body, upper limbs, and trunk. FM (%) and the LTM/FM ratio decreased only in the trunk in men and the lower limbs in women, but the gender difference was only observed for the trunk. In women, age was positively correlated with relative FM variation (% and kg) in the lower limbs and negatively correlated with LTM and LTM/FM. In men, weight was negatively correlated with the relative LTM and FM (kg) variations in the upper limbs. CONCLUSION: SG induces acute weight loss, but this loss comprises losses in both FM and LTM. Because excessive LTM loss can have deleterious consequences, preventive strategies should be implemented soon after bariatric surgery. The specific changes in BC are highlighted according to gender and anatomic site.
BACKGROUND: Sleeve gastrectomy (SG) induces acute weight loss, but its impact on the very early postoperative changes in body composition (BC) is less clear. OBJECTIVES: This longitudinal study examined the BC changes in the first month after SG according to gender and anatomic site. METHODS: BC (lean tissue mass [LTM] and fat mass [FM]) were determined by dual-energy x-ray absorptiometry in 41 obesepatients (33 women, 80.5%) just before SG and 1 month later. SETTING: University hospital of Montpellier, France. RESULTS: One month after SG, mean weight loss was -9.8±2.6 kg, with a significant decrease in LTM and FM (kg) ranging from -7.3% to 9.5%, depending on site. FM (kg) loss in men exceeded that in women at whole body, upper limbs, and trunk. FM (%) and the LTM/FM ratio decreased only in the trunk in men and the lower limbs in women, but the gender difference was only observed for the trunk. In women, age was positively correlated with relative FM variation (% and kg) in the lower limbs and negatively correlated with LTM and LTM/FM. In men, weight was negatively correlated with the relative LTM and FM (kg) variations in the upper limbs. CONCLUSION: SG induces acute weight loss, but this loss comprises losses in both FM and LTM. Because excessive LTM loss can have deleterious consequences, preventive strategies should be implemented soon after bariatric surgery. The specific changes in BC are highlighted according to gender and anatomic site.
Authors: B Guida; M Cataldi; L Busetto; M L Aiello; M Musella; D Capone; S Parolisi; V Policastro; G Ragozini; A Belfiore Journal: J Endocrinol Invest Date: 2018-03-24 Impact factor: 4.256
Authors: Renata Manoel; Fernanda A Venâncio; Gustavo P S Miguel; Fabiano K Haraguchi; Rogerio G Pedrosa Journal: Obes Surg Date: 2022-04-13 Impact factor: 4.129
Authors: Laurent Maïmoun; Chris Serrand; Thibault Mura; Eric Renard; David Nocca; Patrick Lefebvre; Vincent Boudousq; Antoine Avignon; Denis Mariano-Goulart; Ariane Sultan Journal: Sci Rep Date: 2022-10-07 Impact factor: 4.996