| Literature DB >> 28283042 |
Aimee I Porter1, Rebecca A Erwin-Cohen2, Nancy Twenhafel3, Taylor Chance3, Steven B Yee4, Steven J Kern5, David Norwood6, Laurie J Hartman6, Michael D Parker1, Pamela J Glass1, Luis DaSilva4.
Abstract
Entities:
Year: 2017 PMID: 28283042 PMCID: PMC5346236 DOI: 10.1186/s12985-017-0717-5
Source DB: PubMed Journal: Virol J ISSN: 1743-422X Impact factor: 4.099
Viral Plaque Assay and RT-PCR results in solid tissues from marmosets exposed to aerosolized EEEV
| Tissue | Animal ID (Inhaled Dose, PFU) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| marmoset #1 (2.40 x 101) | marmoset #2 (1.15 x 103) | marmoset #3 (1.2 x 104) | marmoset #4 (9.76 x 104) | marmoset #5 (7.95 x 105) | ||||||
| Plaque Assay (PFU/g) | PCR | Plaque Assay (PFU/g) | PCR | Plaque Assay (PFU/g) | PCR | Plaque Assay (PFU/g) | PCR | Plaque Assay (PFU/g) | PCR | |
| Salivary Gland |
|
|
|
|
|
|
|
|
| - |
| Adrenal Gland |
|
|
|
|
|
|
|
|
| + |
| Pancreas |
|
|
|
|
|
|
|
|
| - |
| Lung |
|
|
|
|
|
|
|
|
| - |
| Spleen |
|
|
|
|
|
|
|
|
| - |
| Axillary LN |
|
|
|
|
|
|
|
|
| - |
| Kidney |
|
|
|
|
|
|
|
|
| - |
| Brain |
|
|
|
|
|
|
|
|
| + |
| Heart |
|
|
|
|
|
|
|
|
| + |
| Liver |
|
|
|
|
|
|
|
|
| + |
| Inguinal LN |
|
|
|
|
|
|
|
|
| - |
| Mandibular LN |
|
|
|
|
|
|
|
|
| - |
| Tracheo-bronchial LN |
|
|
|
|
|
|
|
|
| + |
| Mesentric LN |
|
|
|
|
|
|
|
|
| + |
| Popliteal LN |
|
|
|
|
|
|
|
|
| - |
NT no tissue
+ positive assay result, − = negative assay result