Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Immunohistochemical study of angiotensin-converting enzyme in human tissues using monoclonal antibodies.

Literature DB >> 2828286

Immunohistochemical study of angiotensin-converting enzyme in human tissues using monoclonal antibodies.

S M Danilov¹, A I Faerman, A V Martynov, I N Trakht.

Abstract

The localization of angiotensin-converting enzyme (ACE) in human tissues has been studied by the PAP-method with the use of monoclonal antibody 9 B9 against human lung ACE. The enzyme was detected on the surface of endothelial cells in lung, myocardium, liver, intestine and testis as well as in the epithelial cells of the kidney proximal tubules and intestine. The monoclonal antibody 9 B9 did not react with ACE in the epithelial cells of the testis seminiferous tubules. These data suggest that the antibody 9 B9 recognizes epitope which is shared by the ACE molecule of endothelial cells and renal and intestinal epithelial cells but is not present in testicular ACE, or is not accessible there to the antibody.

Entities: Gene Species

Mesh：

Substances：

Year: 1987 PMID： 2828286 DOI： 10.1007/BF00496822

Source DB: PubMed Journal: Histochemistry ISSN： 0301-5564

22 in total

1. Immunochemical comparison of angiotensin 1 converting enzymes from different rat organs.

Authors: R Polsky-Cynkin; B L Fanburg
Journal: Int J Biochem Date: 1979

2. Monoclonal antibody to human lung angiotensin-converting enzyme.

Authors: S M Danilov; E A Dukhanina; I N Trakht
Journal: Biotechnol Appl Biochem Date: 1987-08 Impact factor: 2.431

Review 3. The endothelial surface and responses to injury.

Authors: U S Ryan
Journal: Fed Proc Date: 1986-02

4. Imidazole increases the sensitivity of the cytochemical reaction for peroxidase with diaminobenzidine at a neutral pH.

Authors: W Straus
Journal: J Histochem Cytochem Date: 1982-05 Impact factor: 2.479

5. Development of competitive enzyme immunoassays for human serum angiotensin-1-converting enzyme: a comparison of four assay configurations.

Authors: J J Lanzillo; B L Fanburg
Journal: Anal Biochem Date: 1982-10 Impact factor: 3.365

6. Structure and functions of human angiotensin I converting enzyme (kininase II).

Authors: E G Erdös; R A Skidgel
Journal: Biochem Soc Trans Date: 1985-02 Impact factor: 5.407

7. Monoclonal antibody against angiotensin-converting enzyme: its use as a marker for murine, bovine, and human endothelial cells.

Authors: R Auerbach; L Alby; J Grieves; J Joseph; C Lindgren; L W Morrissey; Y A Sidky; M Tu; S L Watt
Journal: Proc Natl Acad Sci U S A Date: 1982-12 Impact factor: 11.205

8. Angiotensin-converting enzyme in the male rat reproductive system: autoradiographic visualization with [3H]captopril.

Authors: S M Strittmatter; S H Snyder
Journal: Endocrinology Date: 1984-12 Impact factor: 4.736

9. Angiotensin-converting enzyme: immunologic, structural, and developmental aspects.

Authors: R L Soffer; H A El-Dorry
Journal: Fed Proc Date: 1983-07

10. Lung injury mediated by antibodies to endothelium. I. In the rabbit a repeated interaction of heterologous anti-angiotensin-converting enzyme antibodies with alveolar endothelium results in resistance to immune injury through antigenic modulation.

Authors: L M Barba; P R Caldwell; G H Downie; G Camussi; J R Brentjens; G Andres
Journal: J Exp Med Date: 1983-12-01 Impact factor: 14.307

17 in total

1. Inflammatory pseudotumor of lymph nodes. Immunohistochemical evidence for its fibrohistiocytic nature.

Authors: F Facchetti; C De Wolf Peeters; I De Wever; G Frizzera
Journal: Am J Pathol Date: 1990-08 Impact factor: 4.307

2. Inhibition of ACE activity contributes to the intestinal structural compensation in a massive intestinal resection rat model.

Authors: Wensheng Wang; Weidong Xiao; Lihua Sun; Chaojun Zhang; Guoqing Chen; Hua Yang
Journal: Pediatr Surg Int Date: 2012-03-24 Impact factor: 1.827

3. Intestinal intraepithelial lymphocyte derived angiotensin converting enzyme modulates epithelial cell apoptosis.

Authors: B E Wildhaber; H Yang; E Q Haxhija; A U Spencer; D H Teitelbaum
Journal: Apoptosis Date: 2005-12 Impact factor: 4.677

Review 4. Intratubular and intracellular renin-angiotensin system in the kidney: a unifying perspective in blood pressure control.

Authors: Xiao C Li; Dongmin Zhu; Xiaowen Zheng; Jiangfeng Zhang; Jia L Zhuo
Journal: Clin Sci (Lond) Date: 2018-07-09 Impact factor: 6.124

Review 5. A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzyme.

Authors: Kenneth E Bernstein; Frank S Ong; Wendell-Lamar B Blackwell; Kandarp H Shah; Jorge F Giani; Romer A Gonzalez-Villalobos; Xiao Z Shen; Sebastien Fuchs; Rhian M Touyz
Journal: Pharmacol Rev Date: 2012-12-20 Impact factor: 25.468

6. A comparison of the zinc contents and substrate specificities of the endothelial and testicular forms of porcine angiotensin converting enzyme and the preparation of isoenzyme-specific antisera.

Authors: T A Williams; K Barnes; A J Kenny; A J Turner; N M Hooper
Journal: Biochem J Date: 1992-12-15 Impact factor: 3.857

7. Increased angiotensin-I converting enzyme gene expression in the failing human heart. Quantification by competitive RNA polymerase chain reaction.

Authors: R Studer; H Reinecke; B Müller; J Holtz; H Just; H Drexler
Journal: J Clin Invest Date: 1994-07 Impact factor: 14.808