Lucie Griffon1, Alessandro Amaddeo1,2,3, Jorge Olmo Arroyo1, Rossana Tenconi1, Serena Caggiano1, Sonia Khirani1,4, Brigitte Fauroux5,6,7. 1. AP-HP, Hôpital Necker Enfants-Malades, Pediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker, 149 rue de Sèvres, 75015, Paris, France. 2. Paris Descartes University, Paris, France. 3. Research unit INSERM U 955, team 13, Créteil, France. 4. ASV Santé, Gennevilliers, France. 5. AP-HP, Hôpital Necker Enfants-Malades, Pediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker, 149 rue de Sèvres, 75015, Paris, France. brigitte.fauroux@aphp.fr. 6. Paris Descartes University, Paris, France. brigitte.fauroux@aphp.fr. 7. Research unit INSERM U 955, team 13, Créteil, France. brigitte.fauroux@aphp.fr.
Abstract
PURPOSE: The characterization of apneas during polysomnography (PSG) as obstructive or central is a key element of a sleep study. Pulse transit time (PTT) has demonstrated its potential as a noninvasive surrogate marker for inspiratory efforts. The aim of the study was to assess the ability of PTT to classify apneas as central or obstructive, as compared to respiratory inductance plethysmography (RIP) in children. METHODS: Overnight PSG with simultaneous PTT recording was performed on 11 consecutive children (mean age 8.9 years, range 1-18.2 years). The same observer scored the apneas using two blinded configurations: (1) the RIP scoring used the nasal pressure, thermistors, thoracic and abdominal movements, and pulse oximetry signals: (2) the PTT scoring used PTT in combination with all the other signals without the thoracic and abdominal movements. RESULTS: One hundred fourteen apneas out of a total of 520 respiratory events were analyzed. With RIP, 58 (51%) apneas were scored as obstructive and 56 (49%) as central. Using PTT, 77 (68%) of the apneas were scored as obstructive and 37 (32%) as central. When using PTT, 30 apneas scored as central by RIP were scored as obstructive. PTT was highly sensitive (81%) but poorly specific (46%) in scoring 58 apneas as obstructive. PTT was less sensitive (46%) but highly specific (81%) to score 56 apneas as central. CONCLUSION: PTT may be used as an additional tool to RIP to improve the scoring of apneas as obstructive or central in children. The high percentage of artifact is a limitation of PTT.
PURPOSE: The characterization of apneas during polysomnography (PSG) as obstructive or central is a key element of a sleep study. Pulse transit time (PTT) has demonstrated its potential as a noninvasive surrogate marker for inspiratory efforts. The aim of the study was to assess the ability of PTT to classify apneas as central or obstructive, as compared to respiratory inductance plethysmography (RIP) in children. METHODS: Overnight PSG with simultaneous PTT recording was performed on 11 consecutive children (mean age 8.9 years, range 1-18.2 years). The same observer scored the apneas using two blinded configurations: (1) the RIP scoring used the nasal pressure, thermistors, thoracic and abdominal movements, and pulse oximetry signals: (2) the PTT scoring used PTT in combination with all the other signals without the thoracic and abdominal movements. RESULTS: One hundred fourteen apneas out of a total of 520 respiratory events were analyzed. With RIP, 58 (51%) apneas were scored as obstructive and 56 (49%) as central. Using PTT, 77 (68%) of the apneas were scored as obstructive and 37 (32%) as central. When using PTT, 30 apneas scored as central by RIP were scored as obstructive. PTT was highly sensitive (81%) but poorly specific (46%) in scoring 58 apneas as obstructive. PTT was less sensitive (46%) but highly specific (81%) to score 56 apneas as central. CONCLUSION: PTT may be used as an additional tool to RIP to improve the scoring of apneas as obstructive or central in children. The high percentage of artifact is a limitation of PTT.
Authors: Jong Yong A Foo; Stephen J Wilson; Gordon R Williams; Margaret-Ann Harris; David M Cooper Journal: J Clin Monit Comput Date: 2008-08-21 Impact factor: 2.502
Authors: Jong Yong A Foo; Stephen J Wilson; Andrew P Bradley; Gordon R Williams; Margaret-Anne Harris; David M Cooper Journal: Chest Date: 2005-10 Impact factor: 9.410
Authors: Michael P Yanney; Andrew P Prayle; Nicola J Rowbotham; Miguel Kurc; Sean Tilbrook; Nabeel Ali Journal: Front Neurol Date: 2020-05-08 Impact factor: 4.003