Geoffrey J Hoffman1, Ron D Hays2, Steven P Wallace3, Martin F Shapiro2, Susan L Ettner4. 1. Department of Systems, Populations and Leadership, University of Michigan School of Nursing, 400 N. Ingalls Street, Room 4352, Ann Arbor, MI 48109, United States. Electronic address: gjh@umich.edu. 2. Division of General Internal Medicine and Health Services Research, UCLA David Geffen School of Medicine, Department of Health Policy and Management, UCLA Fielding School of Public Health, United States. 3. Department of Community Health Sciences, UCLA Fielding School of Public Health, United States. 4. Division of General Internal Medicine and Health Services Research, UCLA David Geffen School of Medicine, United States.
Abstract
RATIONALE: Falls are common among older adults and may be related to depressive symptoms (DS). With advancing age, there is an onset of chronic conditions, sensory impairments, and activity limitations that are associated with falls and with depressive disorders. Prior cross-sectional studies have observed significant associations between DS and subsequent falls as well as between fractures and subsequent clinical depression and DS. OBJECTIVE: The directionality of these observed relationship between falls and DS is in need of elaboration given that cross-sectional study designs can yield biased estimates of the DS-falls relationship. METHODS: Using 2006-2010 Health and Retirement Study data, cross-lagged panel structural equation models were used to evaluate associations between falls and DS among 7233 community-dwelling adults ages ≥65. Structural coefficients between falls and DS (in 2006→2008, 2008→2010) were estimated. RESULTS: A good-fitting model was found: Controlling for baseline (2006) physical functioning, vision, chronic conditions, and social support and neighborhood social cohesion, falls were not associated with subsequent DS, but a 0.5 standard deviation increase in 2006 DS was associated with a 30% increase in fall risk two years later. This DS-falls relationship was no longer significant when use of psychiatric medications, which was positively associated with falls, was included in the model. CONCLUSION: Using sophisticated methods and a large U.S. sample, we found larger magnitudes of effect in the DS-falls relationship than in prior studies-highlighting the risk of falls for older adults with DS. Medical providers might assess older individuals for DS as well as use of psychotropic medications as part of a broadened falls prevention approach. National guidelines for fall risk assessments as well as quality indicators for fall prevention should include assessment for clinical depression.
RATIONALE: Falls are common among older adults and may be related to depressive symptoms (DS). With advancing age, there is an onset of chronic conditions, sensory impairments, and activity limitations that are associated with falls and with depressive disorders. Prior cross-sectional studies have observed significant associations between DS and subsequent falls as well as between fractures and subsequent clinical depression and DS. OBJECTIVE: The directionality of these observed relationship between falls and DS is in need of elaboration given that cross-sectional study designs can yield biased estimates of the DS-falls relationship. METHODS: Using 2006-2010 Health and Retirement Study data, cross-lagged panel structural equation models were used to evaluate associations between falls and DS among 7233 community-dwelling adults ages ≥65. Structural coefficients between falls and DS (in 2006→2008, 2008→2010) were estimated. RESULTS: A good-fitting model was found: Controlling for baseline (2006) physical functioning, vision, chronic conditions, and social support and neighborhood social cohesion, falls were not associated with subsequent DS, but a 0.5 standard deviation increase in 2006 DS was associated with a 30% increase in fall risk two years later. This DS-falls relationship was no longer significant when use of psychiatric medications, which was positively associated with falls, was included in the model. CONCLUSION: Using sophisticated methods and a large U.S. sample, we found larger magnitudes of effect in the DS-falls relationship than in prior studies-highlighting the risk of falls for older adults with DS. Medical providers might assess older individuals for DS as well as use of psychotropic medications as part of a broadened falls prevention approach. National guidelines for fall risk assessments as well as quality indicators for fall prevention should include assessment for clinical depression.
Authors: L F Berkman; C S Berkman; S Kasl; D H Freeman; L Leo; A M Ostfeld; J Cornoni-Huntley; J A Brody Journal: Am J Epidemiol Date: 1986-09 Impact factor: 4.897
Authors: Jolanda C M van Haastregt; G A Rixt Zijlstra; Erik van Rossum; Jacques Th M van Eijk; Gertrudis I J M Kempen Journal: Am J Geriatr Psychiatry Date: 2008-03 Impact factor: 4.105
Authors: Suzanne E Bentler; Li Liu; Maksym Obrizan; Elizabeth A Cook; Kara B Wright; John F Geweke; Elizabeth A Chrischilles; Claire E Pavlik; Robert B Wallace; Robert L Ohsfeldt; Michael P Jones; Gary E Rosenthal; Fredric D Wolinsky Journal: Am J Epidemiol Date: 2009-10-04 Impact factor: 4.897
Authors: Natália B Moreira; Paulo C B Bento; Edgar Ramos Vieira; José L P da Silva; André L F Rodacki Journal: Int J Environ Res Public Health Date: 2022-06-29 Impact factor: 4.614
Authors: Tommi Vilpunaho; Heikki Kröger; Risto Honkanen; Heli Koivumaa-Honkanen; Joonas Sirola; Virpi Kuvaja-Köllner; Reijo Sund; Toni Rikkonen Journal: BMJ Open Date: 2019-06-21 Impact factor: 2.692
Authors: Gabrielle B Britton; Sid E O'Bryant; Leigh A Johnson; James R Hall; Alcibiades E Villarreal; Diana C Oviedo; Ambar R Pérez-Lao; María B Carreira Journal: Curr Aging Sci Date: 2019