C Wintenberger1, B Guery2, E Bonnet3, B Castan4, R Cohen5, S Diamantis6, P Lesprit7, L Maulin8, Y Péan9, E Peju10, L Piroth10, J P Stahl11, C Strady12, E Varon13, F Vuotto2, R Gauzit14. 1. Département de médecine interne, CHU de Grenoble Alpes, 38043 Grenoble, France. 2. Service de maladies infectieuses, CHU vaudois et université de Lausanne, Lausanne, Switzerland. 3. Équipe mobile d'infectiologie, hôpital Joseph-Ducuing, 15, rue Varsovie, 31300 Toulouse, France. 4. Unité fonctionnelle d'infectiologie régionale, hôpital Eugenie, boulevard Rossini, 20000 Ajaccio, France. 5. IMRB-GRC GEMINI, unité Court Séjour, université Paris Est, Petits Nourrissons, centre hospitalier intercommunal de Créteil, ACTIV France, 40, avenue de Verdun, 94000 Créteil, France. 6. Service de maladies infectieuses et tropicales, centre hospitalier de Melun, 2, rue Fréteau-de-Peny, 77011 Melun cedex, France. 7. Infectiologie transversale, hôpital Foch, 40, rue Worth, 92151 Suresnes, France. 8. Centre hospitalier du Pays-d'Aix, avenue de Tamaris, 13616 Aix-en-Provence, France. 9. Observatoire national de l'épidémiologie de la résistance bactérienne aux antibiotiques (ONERBA), 10, rue de la Bonne-Aventure, 78000 Versailles, France. 10. Département d'infectiologie, CHU de Dijon, 14, rue Gaffarel, 21079 Dijon cedex, France. 11. Infectiologie, université, CHU de Grenoble Alpes, 38043 Grenoble, France. 12. Cabinet d'infectiologie, clinique Saint-André, groupe Courlancy, 5, boulevard de la Paix, 51100 Reims, France. 13. Laboratoire de microbiologie, hôpital européen Georges-Pompidou, 75908 Paris cedex 15, France. 14. Réanimation et infectiologie transversale, hôpital Cochin, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France. Electronic address: remy.gauzit@aphp.fr.
Abstract
OBJECTIVES: Reducing antibiotic consumption has now become a major public health priority. Reducing treatment duration is one of the means to achieve this objective. Guidelines on the therapeutic management of the most frequent infections recommend ranges of treatment duration in the ratio of one to two. The Recommendation Group of the French Infectious Diseases Society (SPILF) was asked to collect literature data to then recommend the shortest treatment durations possible for various infections. METHODS: Analysis of the literature focused on guidelines published in French and English, supported by a systematic search on PubMed. Articles dating from one year before the guidelines publication to August 31, 2015 were searched on the website. RESULTS: The shortest treatment durations based on the relevant clinical data were suggested for upper and lower respiratory tract infections, central venous catheter-related and uncomplicated primary bacteremia, infective endocarditis, bacterial meningitis, intra-abdominal, urinary tract, upper reproductive tract, bone and joint, skin and soft tissue infections, and febrile neutropenia. Details of analyzed articles were shown in tables. CONCLUSION: This work stresses the need for new well-conducted studies evaluating treatment durations for some common infections. Following the above-mentioned work focusing on existing literature data, the Recommendation Group of the SPILF suggests specific study proposals.
OBJECTIVES: Reducing antibiotic consumption has now become a major public health priority. Reducing treatment duration is one of the means to achieve this objective. Guidelines on the therapeutic management of the most frequent infections recommend ranges of treatment duration in the ratio of one to two. The Recommendation Group of the French Infectious Diseases Society (SPILF) was asked to collect literature data to then recommend the shortest treatment durations possible for various infections. METHODS: Analysis of the literature focused on guidelines published in French and English, supported by a systematic search on PubMed. Articles dating from one year before the guidelines publication to August 31, 2015 were searched on the website. RESULTS: The shortest treatment durations based on the relevant clinical data were suggested for upper and lower respiratory tract infections, central venous catheter-related and uncomplicated primary bacteremia, infective endocarditis, bacterial meningitis, intra-abdominal, urinary tract, upper reproductive tract, bone and joint, skin and soft tissue infections, and febrile neutropenia. Details of analyzed articles were shown in tables. CONCLUSION: This work stresses the need for new well-conducted studies evaluating treatment durations for some common infections. Following the above-mentioned work focusing on existing literature data, the Recommendation Group of the SPILF suggests specific study proposals.
Authors: Maria Dudareva; Michelle Kümin; Werner Vach; Klaus Kaier; Jamie Ferguson; Martin McNally; Matthew Scarborough Journal: Trials Date: 2019-12-09 Impact factor: 2.279
Authors: W Pamoda Thavish D Perera; D M Ranga K Dissanayake; Janitha M Unagolla; Rangika T De Silva; Sanjaya D N K Bathige; Lakshitha R Pahalagedara Journal: RSC Adv Date: 2022-01-11 Impact factor: 3.361