| Literature DB >> 28279414 |
Abstract
The number of cancer survivors increases annually, because of advances in detection and treatment, and the aging and growth of the population. This increase has brought a concomitant increase in morbidity and mortality from other conditions related to the adverse effects of cancer treatments. Cardiovascular diseases, and in particular left ventricular dysfunction and heart failure, are among the most significant of these. There are no unified and universally accepted evidence-based practice guidelines on the management of heartfailure in this population. This article discusses the epidemiologic impact of cancer therapeutics-related cardiac dysfunction, and reviews its most significant mediators and provides a condensed but comprehensive synopsis on its evaluation and management.Entities:
Keywords: Anthracyclines; Cancer; Cardio-oncology; Cardioprotection; Cardiotoxicity; Heart failure; Myocardial dysfunction; Trastuzumab
Mesh:
Substances:
Year: 2017 PMID: 28279414 DOI: 10.1016/j.hfc.2016.12.004
Source DB: PubMed Journal: Heart Fail Clin ISSN: 1551-7136 Impact factor: 3.179