Literature DB >> 28279342

West African Ebola Virus Strains: Unstable and Ready to Invade?

Christopher F Basler1.   

Abstract

Recent studies demonstrate that the Ebola virus glycoprotein (GP) acquired an A82V change during the West Africa epidemic and that this change altered the capacity of GP to be activated by host factors, enhancing infection of human cells. How this may alter the outcome of disease remains to be determined.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID: 28279342     DOI: 10.1016/j.chom.2017.02.017

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN: 1931-3128            Impact factor:   21.023


  1 in total

1.  Recently Identified Mutations in the Ebola Virus-Makona Genome Do Not Alter Pathogenicity in Animal Models.

Authors:  Andrea Marzi; Spencer Chadinah; Elaine Haddock; Friederike Feldmann; Nicolette Arndt; Cynthia Martellaro; Dana P Scott; Patrick W Hanley; Tolbert G Nyenswah; Samba Sow; Moses Massaquoi; Heinz Feldmann
Journal:  Cell Rep       Date:  2018-05-08       Impact factor: 9.423

  1 in total

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