| Literature DB >> 28278615 |
Mina Saeedi1,2, Khatereh Babaie3, Elahe Karimpour-Razkenari2, Mahdi Vazirian3, Tahmineh Akbarzadeh2,4, Mahnaz Khanavi2,3, Mannan Hajimahmoodi2,5, Mohammad Reza Shams Ardekani2,3.
Abstract
In this study, in vitro evaluation of cholinesterase inhibitory (ChEI) activity of various plants including betel nuts (Areca catechu L.), clove buds (Syzygium aromaticum L.), aerial parts of dodder (Cuscuta chinensis Lam.), common polypody rhizomes (Polypodium vulgare L.) and turpeth roots (Ipomoea turpethum R. Br.) which were recommended for the treatment of AD symptoms in Iranian Traditional Medicine (ITM) is reported. Among them, aqueous extract of A. catechu L. was found as the most potent anti-AChE (IC50 = 32.00 μg/mL) and anti-BChE (IC50 = 48.81 ± 0.1200 μg/mL) agent.Entities:
Keywords: A. catechu; C. chinensis; Cholinesterase inhibitors; I. turpethum; Iranian traditional medicine; P. vulgare; S. aromaticum
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Year: 2017 PMID: 28278615 DOI: 10.1080/14786419.2017.1290620
Source DB: PubMed Journal: Nat Prod Res ISSN: 1478-6419 Impact factor: 2.861