Literature DB >> 28276808

Caspase inhibitors for the treatment of liver disease: friend or foe?

Benjamin L Woolbright1, Wen-Xing Ding1, Hartmut Jaeschke1.   

Abstract

Entities:  

Keywords:  Apoptosis; TNF-alpha; acetaminophen; caspase inhibitors; cholestasis; galactosamine-endotoxin; hepatotoxicity; ischemia-reperfusion; necroptosis

Mesh：

Substances：

Year:  2017        PMID： 28276808      PMCID： PMC5493036          DOI： 10.1080/17474124.2017.1300060

Source DB:  PubMed          Journal:  Expert Rev Gastroenterol Hepatol        ISSN： 1747-4124            Impact factor:   3.869


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  25 in total

1.  Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.

Authors:  Benjamin L Woolbright; Kenneth Dorko; Daniel J Antoine; Joanna I Clarke; Parviz Gholami; Feng Li; Sean C Kumer; Timothy M Schmitt; Jameson Forster; Fang Fan; Rosalind E Jenkins; B Kevin Park; Bruno Hagenbuch; Mojtaba Olyaee; Hartmut Jaeschke
Journal:  Toxicol Appl Pharmacol       Date:  2015-01-28       Impact factor: 4.219

2.  Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase.

Authors:  Liming Sun; Huayi Wang; Zhigao Wang; Sudan He; She Chen; Daohong Liao; Lai Wang; Jiacong Yan; Weilong Liu; Xiaoguang Lei; Xiaodong Wang
Journal:  Cell       Date:  2012-01-20       Impact factor: 41.582

Review 3.  Inflammasomes in liver diseases.

Authors:  Gyongyi Szabo; Timea Csak
Journal:  J Hepatol       Date:  2012-05-23       Impact factor: 25.083

Review 4.  Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury.

Authors:  Hartmut Jaeschke; John J Lemasters
Journal:  Gastroenterology       Date:  2003-10       Impact factor: 22.682

Review 5.  Novel insight into mechanisms of cholestatic liver injury.

Authors:  Benjamin L Woolbright; Hartmut Jaeschke
Journal:  World J Gastroenterol       Date:  2012-09-28       Impact factor: 5.742

6.  Caspase Inhibition Prevents Tumor Necrosis Factor-α-Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in Vivo and in Vitro.

Authors:  Hong-Min Ni; Mitchell R McGill; Xiaojuan Chao; Benjamin L Woolbright; Hartmut Jaeschke; Wen-Xing Ding
Journal:  Am J Pathol       Date:  2016-09-09       Impact factor: 4.307

7.  Cystatin A expression reduces bile salt-induced apoptosis in a rat hepatoma cell line.

Authors:  B Jones; P J Roberts; W A Faubion; E Kominami; G J Gores
Journal:  Am J Physiol       Date:  1998-10

8.  Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha.

Authors:  Sudan He; Lai Wang; Lin Miao; Tao Wang; Fenghe Du; Liping Zhao; Xiaodong Wang
Journal:  Cell       Date:  2009-06-12       Impact factor: 41.582

9.  The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs.

Authors:  Tencho Tenev; Katiuscia Bianchi; Maurice Darding; Meike Broemer; Claudia Langlais; Fredrik Wallberg; Anna Zachariou; Juanita Lopez; Marion MacFarlane; Kelvin Cain; Pascal Meier
Journal:  Mol Cell       Date:  2011-07-07       Impact factor: 17.970

Review 10.  New horizons in hepatitis C antiviral therapy with direct-acting antivirals.

Authors:  Alessio Aghemo; Raffaele De Francesco
Journal:  Hepatology       Date:  2013-05-31       Impact factor: 17.425
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  9 in total

1.  Phenotypic high-throughput screening platform identifies novel chemotypes for necroptosis inhibition.

Authors:  Hugo Brito; Vanda Marques; Marta B Afonso; Dean G Brown; Ulf Börjesson; Nidhal Selmi; David M Smith; Ieuan O Roberts; Martina Fitzek; Natália Aniceto; Rita C Guedes; Rui Moreira; Cecília M P Rodrigues
Journal:  Cell Death Discov       Date:  2020-02-11

2.  Strategies Targeting the Innate Immune Response for the Treatment of Hepatitis C Virus-Associated Liver Fibrosis.

Authors:  Daniel Sepulveda-Crespo; Salvador Resino; Isidoro Martinez
Journal:  Drugs       Date:  2021-01-05       Impact factor: 9.546

3.  Is Keratin-18 only a Marker of Cell Death in Acute-On-Chronic Liver Failure?

Authors:  Benjamin L Woolbright; Hartmut Jaeschke
Journal:  J Lab Precis Med       Date:  2018-03-20

Review 4.  Pyroptosis in inflammatory diseases and cancer.

Authors:  Zhiping Rao; Yutong Zhu; Peng Yang; Zhuang Chen; Yuqiong Xia; Chaoqiang Qiao; Weijing Liu; Hongzhang Deng; Jianxiong Li; Pengbo Ning; Zhongliang Wang
Journal:  Theranostics       Date:  2022-05-16       Impact factor: 11.600

5.  Emricasan, a pan-caspase inhibitor, improves survival and portal hypertension in a murine model of common bile-duct ligation.

Authors:  Akiko Eguchi; Yukinori Koyama; Alexander Wree; Casey D Johnson; Ryota Nakamura; Davide Povero; David Kneiber; Masahiko Tameda; Patricia Contreras; Al Spada; Ariel E Feldstein
Journal:  J Mol Med (Berl)       Date:  2018-05-05       Impact factor: 4.599

6.  Phenotypic high-throughput screening platform identifies novel chemotypes for necroptosis inhibition.

Authors:  Hugo Brito; Vanda Marques; Marta B Afonso; Dean G Brown; Ulf Börjesson; Nidhal Selmi; David M Smith; Ieuan O Roberts; Martina Fitzek; Natália Aniceto; Rita C Guedes; Rui Moreira; Cecília M P Rodrigues
Journal:  Cell Death Discov       Date:  2020-02-11

Review 7.  Multi-faceted role of pyroptosis mediated by inflammasome in liver fibrosis.

Authors:  Hui Yang; Juan Wang; Zhen-Guo Liu
Journal:  J Cell Mol Med       Date:  2022-04-12       Impact factor: 5.295

8.  Synthesis, Characterization, and In Vivo Study of Some Novel 3,4,5-Trimethoxybenzylidene-hydrazinecarbothioamides and Thiadiazoles as Anti-Apoptotic Caspase-3 Inhibitors.

Authors:  Sara M Mostafa; Ashraf A Aly; Stefan Bräse; Martin Nieger; Sara Mohamed Naguib Abdelhafez; Walaa Yehia Abdelzaher; El-Shimaa M N Abdelhafez
Journal:  Molecules       Date:  2022-03-31       Impact factor: 4.927

9.  Metabolomics Reveals the Efficacy of Caspase Inhibition for Saikosaponin D-Induced Hepatotoxicity.

Authors:  Qian-Qian Zhang; Wan-Qiu Huang; Yi-Qiao Gao; Zhao-di Han; Wei Zhang; Zun-Jian Zhang; Feng-Guo Xu
Journal:  Front Pharmacol       Date:  2018-07-06       Impact factor: 5.810
  9 in total

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