Literature DB >> 28275605

Unrelenting Ocular Pain as a Masquerading Symptom of Occult Choroidal Metastasis.

Jordan D Deaner1, Renelle Pointdujour-Lim1, Emil Anthony T Say1, Carol L Shields1.   

Abstract

PURPOSE: To report a case of chronic eye pain as a presenting feature of choroidal metastasis from lung cancer.
METHODS: We report the case of a 58-year-old Caucasian woman with stage IV lung adenocarcinoma presenting with an 8-month history of left eye pain and blurred vision.
RESULTS: The patient had previously consulted 14 ophthalmologists with varying diagnoses including posterior scleritis and trigeminal neuralgia. Visual acuity at presentation was 20/20 in the right eye and 20/80 in the left eye. Examination of the right eye was normal, while the left eye showed ill-defined flat yellow discoloration of the choroid with overlying shifting subretinal fluid. Ultrasonography demonstrated a dense choroidal thickening measuring 2.6 mm in size and showing subretinal fluid. Enhanced depth imaging optical coherence tomography revealed choroidal thickening with a 'lumpy bumpy' surface topography consistent with a metastatic choroidal tumor presumably from the patient's lung adenocarcinoma. Fine needle aspiration biopsy followed by treatment was recommended, but the patient declined and later succumbed to metastatic disease.
CONCLUSION: We present a case of chronic eye pain associated with diffuse choroidal thickening from metastatic lung adenocarcinoma that was previously unrecognized and misdiagnosed. This case emphasizes the importance of recognizing pain as a presenting symptom of choroidal metastasis.

Entities:  

Keywords:  Choroidal metastasis; Lung carcinoma; Ocular pain; Scleritis

Year:  2016        PMID: 28275605      PMCID: PMC5318930          DOI: 10.1159/000448720

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  13 in total

1.  Posterior scleritis: clinical features, systemic associations, and outcome in a large series of patients.

Authors:  P J McCluskey; P G Watson; S Lightman; J Haybittle; M Restori; M Branley
Journal:  Ophthalmology       Date:  1999-12       Impact factor: 12.079

2.  Headache or eye pain as the presenting feature of uveal melanoma.

Authors:  Pukhraj Rishi; Carol L Shields; Mohammed Ali Khan; Kaitlin Patrick; Jerry A Shields
Journal:  Ophthalmology       Date:  2013-09       Impact factor: 12.079

3.  Pain of ocular and periocular origin.

Authors:  Corey W Waldman; Steven D Waldman; Reid A Waldman
Journal:  Med Clin North Am       Date:  2012-12-22       Impact factor: 5.456

4.  Posterior scleritis: clinical profile and imaging characteristics.

Authors:  J Biswas; S Mittal; S K Ganesh; N S Shetty; L Gopal
Journal:  Indian J Ophthalmol       Date:  1998-12       Impact factor: 1.848

5.  Ocular pain: a casualty study. The spectrum and prevalence of pain in acute eye disease.

Authors:  C J Roberts; J D MacLeod; A R Elkington
Journal:  Eye (Lond)       Date:  1997       Impact factor: 3.775

6.  Choroidal observations in posterior scleritis using high-penetration optical coherence tomography.

Authors:  Hiroaki Uchihori; Kei Nakai; Yasushi Ikuno; Fumi Gomi; Noriyasu Hashida; Yukari Jo; Kohji Nishida
Journal:  Int Ophthalmol       Date:  2014-01-08       Impact factor: 2.031

7.  Survey of 520 eyes with uveal metastases.

Authors:  C L Shields; J A Shields; N E Gross; G P Schwartz; S E Lally
Journal:  Ophthalmology       Date:  1997-08       Impact factor: 12.079

8.  Uveal metastasis from lung cancer: clinical features, treatment, and outcome in 194 patients.

Authors:  Sanket U Shah; Arman Mashayekhi; Carol L Shields; Harpreet S Walia; G Baker Hubbard; Junjun Zhang; Jerry A Shields
Journal:  Ophthalmology       Date:  2013-08-26       Impact factor: 12.079

Review 9.  Painful ophthalmologic disorders and eye pain for the neurologist.

Authors:  Andrew G Lee; Hilary A Beaver; Paul W Brazis
Journal:  Neurol Clin       Date:  2004-02       Impact factor: 3.806

Review 10.  An update on eye pain for the neurologist.

Authors:  Andrew G Lee; Nagham Al-Zubidi; Hilary A Beaver; Paul W Brazis
Journal:  Neurol Clin       Date:  2014-02-28       Impact factor: 3.806

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