Literature DB >> 28275414

Paraoxonase 1 - an Update of the Antioxidant Properties of High- Density Lipoproteins.

Bogdan Nicolae Manolescu1, Carmina Busu2, Daniela Badita3, Ruxandra Stanculescu4, Mihai Berteanu5.   

Abstract

Paraoxonase 1 (PON1) belongs to a family of enzymes with related functions, being the best studied member. PON1 is a HDL-associated protein of which function is to protect LDL particles from oxidative modifications. The status of PON1 is influenced by different genetic, life style and dietary factors. This short review is aimed to present some new aspects regarding the antioxidant properties of PON1 with emphasis on the influence exerted by different factors. Also, a special attention is paid to the relationship between PON1 and low- and high-density lipoproteins in the context of atherosclerosis which affects the endothelial cells.

Entities:  

Year:  2015        PMID： 28275414      PMCID： PMC5327813     

Source DB:  PubMed          Journal:  Maedica (Buchar)        ISSN： 1841-9038


  35 in total

Review 1.  The antioxidant properties of high-density lipoproteins in atherosclerosis.

Authors:  B Mackness; M Mackness
Journal:  Panminerva Med       Date:  2012-06       Impact factor: 5.197

Review 2.  Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: the hunt goes on.

Authors:  Lucio G Costa; Gennaro Giordano; Clement E Furlong
Journal:  Biochem Pharmacol       Date:  2010-11-18       Impact factor: 5.858

Review 3.  Paraoxonases: ancient substrate hunters and their evolving role in ischemic heart disease.

Authors:  Nicola Martinelli; Letizia Consoli; Domenico Girelli; Elisa Grison; Roberto Corrocher; Oliviero Olivieri
Journal:  Adv Clin Chem       Date:  2013       Impact factor: 5.394

4.  Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities.

Authors:  Dragomir I Draganov; John F Teiber; Audrey Speelman; Yoichi Osawa; Roger Sunahara; Bert N La Du
Journal:  J Lipid Res       Date:  2005-03-16       Impact factor: 5.922

5.  The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.

Authors:  S L Primo-Parmo; R C Sorenson; J Teiber; B N La Du
Journal:  Genomics       Date:  1996-05-01       Impact factor: 5.736

6.  Paraoxonase 1 (PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: a role for PPAR-gamma pathway.

Authors:  Jasmin Khateeb; Anna Gantman; Adam J Kreitenberg; Michael Aviram; Bianca Fuhrman
Journal:  Atherosclerosis       Date:  2009-09-06       Impact factor: 5.162

7.  Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis.

Authors:  D M Shih; L Gu; Y R Xia; M Navab; W F Li; S Hama; L W Castellani; C E Furlong; L G Costa; A M Fogelman; A J Lusis
Journal:  Nature       Date:  1998-07-16       Impact factor: 49.962

8.  Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3.

Authors:  John F Teiber; Dragomir I Draganov; Bert N La Du
Journal:  Biochem Pharmacol       Date:  2003-09-15       Impact factor: 5.858

9.  Total oxidant, antioxidant, and paraoxonase levels in babies born to pre-eclamptic mothers.

Authors:  Hüseyin Altunhan; Ali Annagür; Sevil Kurban; Sabahattin Ertuğrul; Murat Konak; Rahmi Örs
Journal:  J Obstet Gynaecol Res       Date:  2013-04-04       Impact factor: 1.730

10.  Paraoxonase active site required for protection against LDL oxidation involves its free sulfhydryl group and is different from that required for its arylesterase/paraoxonase activities: selective action of human paraoxonase allozymes Q and R.

Authors:  M Aviram; S Billecke; R Sorenson; C Bisgaier; R Newton; M Rosenblat; J Erogul; C Hsu; C Dunlop; B La Du
Journal:  Arterioscler Thromb Vasc Biol       Date:  1998-10       Impact factor: 8.311
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  3 in total

Review 1.  Genetics of Familial Combined Hyperlipidemia (FCHL) Disorder: An Update.

Authors:  Eskandar Taghizadeh; Najmeh Farahani; Rajab Mardani; Forough Taheri; Hassan Taghizadeh; Seyed Mohammad Gheibihayat
Journal:  Biochem Genet       Date:  2021-09-03       Impact factor: 1.890

2.  Low Serum Paraoxonase-1 Activity Associates with Incident Cardiovascular Disease Risk in Subjects with Concurrently High Levels of High-Density Lipoprotein Cholesterol and C-Reactive Protein.

Authors:  James P Corsetti; Charles E Sparks; Richard W James; Stephan J L Bakker; Robin P F Dullaart
Journal:  J Clin Med       Date:  2019-09-01       Impact factor: 4.241

3.  Altered redox status may contribute to aberrant folliculogenesis and poor reproductive outcomes in women with polycystic ovary syndrome.

Authors:  Aalaap Naigaonkar; Roshan Dadachanji; Indira Hinduja; Srabani Mukherjee
Journal:  J Assist Reprod Genet       Date:  2021-05-26       Impact factor: 3.357
  3 in total

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