Literature DB >> 28274984

Development of a postgraduate year 2 pharmacy residency in clinical pharmacogenetics.

Cyrine E Haidar1, James M Hoffman2, Roseann S Gammal2, Mary V Relling2, Kristine R Crews2.   

Abstract

PURPOSE: The structure and development of an innovative, ASHP-accredited postgraduate year 2 (PGY2) clinical pharmacogenetics residency program are described.
SUMMARY: A 12-month PGY2 clinical pharmacogenetics residency was created at St. Jude Children's Research Hospital in accordance with the ASHP standards for advanced practice residencies. The purpose of this 12-month residency program is to prepare pharmacy residents to implement pharmacogenetics in clinical practice. The program helps residents develop expertise in the science of pharmacogenetics as well as an understanding of translational research, innovative pharmacy practice model development, and clinical informatics. The resident learns to optimize patient outcomes through the expert provision of evidence-based, patient-centered precision medicine as an integral part of an interprofessional team. After completing the program, residents are expected to have the clinical skills necessary to practice in the field of clinical pharmacogenetics and independently implement pharmacogenetic testing in other health-system settings. Because implementation of pharmacogenetics requires collaboration across many disciplines, residents works within an interprofessional team of physicians, nurses, informatics specialists, pharmacists, and clinical laboratory personnel to achieve program goals. Since the first resident graduated in 2012, the program has graduated 1 resident each year. Graduated residents have accepted pharmacogenetics positions at major academic medical centers and community hospitals, as well as academic and research positions with a pharmacogenetics emphasis.
CONCLUSION: A PGY2 clinical pharmacogenetics residency was successfully developed at St. Jude in 2013. After completion of the program, residents are equipped with the clinical skills and necessary experience to drive precision medicine forward and lead the implementation of pharmacogenetic testing in other healthcare settings.
Copyright © 2017 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

Entities:  

Keywords:  pharmacy; residency, pharmacogenomics; residency, pharmacogentics; training

Mesh:

Year:  2017        PMID: 28274984      PMCID: PMC5499519          DOI: 10.2146/ajhp160174

Source DB:  PubMed          Journal:  Am J Health Syst Pharm        ISSN: 1079-2082            Impact factor:   2.637


  18 in total

1.  CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network.

Authors:  M V Relling; T E Klein
Journal:  Clin Pharmacol Ther       Date:  2011-01-26       Impact factor: 6.875

2.  Bold goals for health-system pharmacy: Perspectives of an experienced practice leader.

Authors:  James G Stevenson
Journal:  Am J Health Syst Pharm       Date:  2014-11-15       Impact factor: 2.637

3.  Leading clinical pharmacogenomics implementation: Advancing pharmacy practice.

Authors:  Samuel G Johnson
Journal:  Am J Health Syst Pharm       Date:  2015-08-01       Impact factor: 2.637

4.  ASHP statement on the pharmacist's role in clinical pharmacogenomics.

Authors: 
Journal:  Am J Health Syst Pharm       Date:  2015-04-01       Impact factor: 2.637

Review 5.  Pharmacogenomics in the clinic.

Authors:  Mary V Relling; William E Evans
Journal:  Nature       Date:  2015-10-15       Impact factor: 49.962

6.  PG4KDS: a model for the clinical implementation of pre-emptive pharmacogenetics.

Authors:  James M Hoffman; Cyrine E Haidar; Mark R Wilkinson; Kristine R Crews; Donald K Baker; Nancy M Kornegay; Wenjian Yang; Ching-Hon Pui; Ulrike M Reiss; Aditya H Gaur; Scott C Howard; William E Evans; Ulrich Broeckel; Mary V Relling
Journal:  Am J Med Genet C Semin Med Genet       Date:  2014-03-11       Impact factor: 3.908

Review 7.  Preemptive clinical pharmacogenetics implementation: current programs in five US medical centers.

Authors:  Henry M Dunnenberger; Kristine R Crews; James M Hoffman; Kelly E Caudle; Ulrich Broeckel; Scott C Howard; Robert J Hunkler; Teri E Klein; William E Evans; Mary V Relling
Journal:  Annu Rev Pharmacol Toxicol       Date:  2014-10-02       Impact factor: 13.820

Review 8.  Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing.

Authors:  R S Gammal; M H Court; C E Haidar; O F Iwuchukwu; A H Gaur; M Alvarellos; C Guillemette; J L Lennox; M Whirl-Carrillo; S S Brummel; M J Ratain; T E Klein; B R Schackman; K E Caudle; D W Haas
Journal:  Clin Pharmacol Ther       Date:  2015-11-09       Impact factor: 6.875

Review 9.  Emerging roles for pharmacists in clinical implementation of pharmacogenomics.

Authors:  Aniwaa Owusu-Obeng; Kristin W Weitzel; Randy C Hatton; Benjamin J Staley; Jennifer Ashton; Rhonda M Cooper-Dehoff; Julie A Johnson
Journal:  Pharmacotherapy       Date:  2014-09-15       Impact factor: 4.705

10.  Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process.

Authors:  Kelly E Caudle; Teri E Klein; James M Hoffman; Daniel J Muller; Michelle Whirl-Carrillo; Li Gong; Ellen M McDonagh; Katrin Sangkuhl; Caroline F Thorn; Matthias Schwab; Jose A G Agundez; Robert R Freimuth; Vojtech Huser; Ming Ta Michael Lee; Otito F Iwuchukwu; Kristine R Crews; Stuart A Scott; Mia Wadelius; Jesse J Swen; Rachel F Tyndale; C Michael Stein; Dan Roden; Mary V Relling; Marc S Williams; Samuel G Johnson
Journal:  Curr Drug Metab       Date:  2014-02       Impact factor: 3.731

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  2 in total

1.  Aligning the AACP Strategic Engagement Agenda with Key Federal Priorities in Health: Report of the 2016-17 Argus Commission.

Authors:  Brian Crabtree; J Lyle Bootman; Cynthia J Boyle; Patricia Chase; Peggy Piascik; Lucinda L Maine
Journal:  Am J Pharm Educ       Date:  2017-10       Impact factor: 2.047

2.  Integrating pharmacogenetic testing into primary care.

Authors:  Susanne B Haga
Journal:  Expert Rev Precis Med Drug Dev       Date:  2017-11-03
  2 in total

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