Emmert Roberts1, Leah Jones2, Alexandra Blackman2, Thomas Dewhurst2, Faith Matcham3, Carol Kan4, Omar Mustafa5, Toral Thomas6, Najma Siddiqi7, Khalida Ismail4, Hermione Price8. 1. Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK. Electronic address: emmert.roberts@kcl.ac.uk. 2. South London and Maudsley NHS Foundation Trust, Denmark Hill, London, UK. 3. Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK. 4. Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK. 5. Department of Diabetes, King's College Hospital, Denmark Hill, London, UK. 6. The Herschel Prins Centre, Leicester, UK. 7. Health Sciences, University of York, Hull York Medical School, York, UK; Bradford District Care NHS Foundation Trust, Bradford, UK. 8. West Hampshire Community Diabetes Service, Southern Health NHS Foundation Trust, Pikes Hill, Lyndhurst, UK.
Abstract
OBJECTIVE: To systematically determine the prevalence of diabetes mellitus (DM), impaired fasting glucose (IFG), and impaired glucose tolerance (IGT) in psychiatric inpatients and explore the impact of patient and study variables on prevalence estimates. METHOD: We searched EMBASE, PsychINFO, Medline and CENTRAL from database inception until 1st December 2015. We included studies of any design reporting prevalence of abnormal glucose metabolism in any adult psychiatric inpatients. We conducted a random effects meta-analysis to generate pooled prevalence estimates. Chi-square tests compared differences within categorical variables (inpatient setting, continent of study and patient diagnostic category) and Spearman's correlation analyses assessed the impact of linear variables (age, year of data collection and study quality). Study quality was assessed using an adapted Newcastle-Ottawa Scale. RESULTS: 36 study reports representing 42 unique cohorts were included. Across all studies prevalence of unspecified type DM was 10% (95%CI: 9-12), of T1DM was 1% (0-1), of T2DM was 9% (6-13), of IFG 18% (8-28), and of IGT was 22% (16-28). These estimates were not affected by study quality. CONCLUSIONS: All estimates are higher compared to the general population. Mental health professionals should be aware of this elevated prevalence to improve screening and management of abnormal glucose metabolism.
OBJECTIVE: To systematically determine the prevalence of diabetes mellitus (DM), impaired fasting glucose (IFG), and impaired glucose tolerance (IGT) in psychiatric inpatients and explore the impact of patient and study variables on prevalence estimates. METHOD: We searched EMBASE, PsychINFO, Medline and CENTRAL from database inception until 1st December 2015. We included studies of any design reporting prevalence of abnormal glucose metabolism in any adult psychiatric inpatients. We conducted a random effects meta-analysis to generate pooled prevalence estimates. Chi-square tests compared differences within categorical variables (inpatient setting, continent of study and patient diagnostic category) and Spearman's correlation analyses assessed the impact of linear variables (age, year of data collection and study quality). Study quality was assessed using an adapted Newcastle-Ottawa Scale. RESULTS: 36 study reports representing 42 unique cohorts were included. Across all studies prevalence of unspecified type DM was 10% (95%CI: 9-12), of T1DM was 1% (0-1), of T2DM was 9% (6-13), of IFG 18% (8-28), and of IGT was 22% (16-28). These estimates were not affected by study quality. CONCLUSIONS: All estimates are higher compared to the general population. Mental health professionals should be aware of this elevated prevalence to improve screening and management of abnormal glucose metabolism.
Authors: Nanna Lindekilde; Stine H Scheuer; Femke Rutters; Lenette Knudsen; Mathias Lasgaard; Katrine H Rubin; Jan Erik Henriksen; Mika Kivimäki; Gregers S Andersen; Frans Pouwer Journal: Diabetologia Date: 2021-11-29 Impact factor: 10.122
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Authors: Ana Paula Souto Melo; Ilse N Dippenaar; Sarah Charlotte Johnson; Nicole Davis Weaver; Francisco de Assis Acurcio; Deborah Carvalho Malta; Antônio Luiz P Ribeiro; Augusto Afonso Guerra Júnior; Eve E Wool; Mohsen Naghavi; Mariangela Leal Cherchiglia Journal: Lancet Psychiatry Date: 2022-08-11 Impact factor: 77.056