Literature DB >> 28274004

Triple Synchronous Malignancies in Genital Tract; Primary Endometrial, Ovarian and Fallopian Tube Carcinoma: A Case Report.

Ozgur Kan1, Aysegul Alkilic2, Batuhan Turgay3, Ali Gemici1, Cem Somer Atabekoglu4.   

Abstract

Synchronous malignancies, including three or more tumours, are extremely rare. Herein, we present a case of a woman with a concurrent simultaneous endometrial, ovarian and fallopian tubal carcinoma with different histopathological characteristics. A 55-year-old postmenopausal woman with a diagnosis of endometrial adenocarcinoma by pipelle biopsy, underwent surgical staging. Final pathology result was reported as synchronous stage IA grade 2 endometrioid adenocarcinoma of the uterus, stage IA grade 2 mucinous adenocarcinoma of the right ovary and in situ serous cystadenocarcinoma of the right fallopian tube. In the postoperative period, patient followed without adjuvant therapy. To our knowledge, this a very rare case report in the literature of sychronous triple gynaecologic cancers including fallopian tube cancer and with the longest disease free survival time with over 39 months due to better prognosis than metastatic or advanced primitive diseases.

Entities:  

Keywords:  Different primaries; Synchronous tumours; Triple cancers

Year:  2017        PMID: 28274004      PMCID: PMC5324449          DOI: 10.7860/JCDR/2017/22003.9138

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  17 in total

1.  Ovarian Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology.

Authors:  Robert J Morgan; Deborah K Armstrong; Ronald D Alvarez; Jamie N Bakkum-Gamez; Kian Behbakht; Lee-May Chen; Larry Copeland; Marta Ann Crispens; Maria DeRosa; Oliver Dorigo; David M Gershenson; Heidi J Gray; Ardeshir Hakam; Laura J Havrilesky; Carolyn Johnston; Shashikant Lele; Lainie Martin; Ursula A Matulonis; David M O'Malley; Richard T Penson; Sanja Percac-Lima; Mario Pineda; Steven C Plaxe; Matthew A Powell; Elena Ratner; Steven W Remmenga; Peter G Rose; Paul Sabbatini; Joseph T Santoso; Theresa L Werner; Jennifer Burns; Miranda Hughes
Journal:  J Natl Compr Canc Netw       Date:  2016-09       Impact factor: 11.908

2.  Multifocal disease in the upper genital canal.

Authors:  J D Woodruff; D Solomon; H Sullivant
Journal:  Obstet Gynecol       Date:  1985-05       Impact factor: 7.661

Review 3.  Triple synchronous invasive malignancies of the female genital tract in a patient with a history of leukemia: A case report and review of the literature.

Authors:  Benito Chiofalo; Jacopo Di Giuseppe; Lara Alessandrini; Tiziana Perin; Giorgio Giorda; Vincenzo Canzonieri; Francesco Sopracordevole
Journal:  Pathol Res Pract       Date:  2016-02-27       Impact factor: 3.250

4.  Four synchronous female genital malignancies: the ovary, cervix, endometrium and fallopian tube.

Authors:  Arzu Saglam; Gurkan Bozdag; Gamze Mocan Kuzey; Turkan Kuçukali; Ali Ayhan
Journal:  Arch Gynecol Obstet       Date:  2008-06       Impact factor: 2.344

5.  The incidence of primary fallopian tube cancer in the United States.

Authors:  Sherri L Stewart; Jennifer M Wike; Stephanie L Foster; Frances Michaud
Journal:  Gynecol Oncol       Date:  2007-10-24       Impact factor: 5.482

6.  Synchronous primary carcinoma in 5 different organs of a female genital tract: an unusual case and review of the literature.

Authors:  Melahat Atasever; Bulent Yilmaz; Gulay Dilek; Eda Yilmaz Akcay; Sefa Kelekci
Journal:  Int J Gynecol Cancer       Date:  2009-05       Impact factor: 3.437

7.  Triple simultaneous primary invasive gynecological malignancies: a case report.

Authors:  Eriko Takatori; Tadahiro Shoji; Yuki Miura; Satoshi Takeuchi; Noriyuki Uesugi; Toru Sugiyama
Journal:  J Obstet Gynaecol Res       Date:  2013-10-22       Impact factor: 1.730

8.  Meta-analysis of BRCA1 and BRCA2 penetrance.

Authors:  Sining Chen; Giovanni Parmigiani
Journal:  J Clin Oncol       Date:  2007-04-10       Impact factor: 44.544

9.  Synchronous primary cancers of the endometrium and ovary.

Authors:  Y-C Chiang; C-A Chen; C-Y Huang; C-Y Hsieh; W-F Cheng
Journal:  Int J Gynecol Cancer       Date:  2007-05-15       Impact factor: 3.437

10.  Synchronous primary ovarian and endometrial cancers: a population-based assessment of survival.

Authors:  Melony G Williams; Elisa V Bandera; Kitaw Demissie; Lorna Rodríguez-Rodríguez
Journal:  Obstet Gynecol       Date:  2009-04       Impact factor: 7.661

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  1 in total

1.  Triple synchronous tumour of female genital tract: cervical squamous cell carcinoma, right ovarian dermoid cyst and left ovarian benign Brenner tumour.

Authors:  Amit Kumar Adhya; Ranjan Mohanty
Journal:  BMJ Case Rep       Date:  2019-07-21
  1 in total

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