Mousumi Datta1, Jhuma Biswas2, Shyamal Dasgupta3, Kaushik Banerjee4, Subhendu Choudhury5, Sandip Kumar Sengupta6, Prakash Das7. 1. Assistant Professor, Department of Community Medicine, Medical College and Hospital , Kolkata, West Bengal, India . 2. Assistant Professor, Department of Obstetrics and Gynaecology, Bankura Sammilani Medical College , Kolkata, West Bengal, India . 3. Associate Professor, Department of Obstetrics and Gynaecology, R.G Kar Medical College , Kolkata, West Bengal, India . 4. Medical Officer, Department of Obstetrics and Gynaecology, Hooghly District Hospital , Hooghly, West Bengal, India . 5. Clinical Tutor, Department of Obstetrics and Gynaecology, IPGMER , Kolkata, West Bengal, India. 6. Assistant Professor, Department of Obstetrics and Gynaecology, North Bengal Medical College , Darjeeling, West Bengal, India . 7. Senior Resident, Department of Obstetrics and Gynaecology, RG Kar Medical College , Kolkata, West Bengal, India .
Abstract
INTRODUCTION: Malaria occurring in pregnancy is associated with considerable maternal and perinatal morbidity. In India, the problem is compounded by dual parasitological aetiology of Plasmodiumvivax (P.vivax) and Plasmodium falciparum (P.falciparum). AIM: To compare the outcome of infections by P. vivax and P.falciparum species among pregnant women in a hospital setting. MATERIALS AND METHODS: Pregnant women who tested positive for malaria either by microscopy of peripheral blood smear or ELISA test for double antigen were enrolled in the study. They were followed up till their delivery and discharge from hospital. Demographic, clinical and laboratory data was collected at enrolment, on event of complication and at delivery. Data was analyzed for univariate and multivariate associations. RESULTS: There were 64 pregnant women diagnosed with malaria. A total of 76.6% study subjects had vivax infection rest were infected with p. falciparum. Anaemia (84%) was the commonest complication. A total of 60.9% women had pathological placenta. Preterm delivery, low birth weight and Apgar score <7 were the adverse pregnancy outcomes which were more frequent with falciparum infection. There were three perinatal deaths. Multigravidas were at significantly higher risk for low birth weight and low Apgar score of newborn. Infection in later trimester was associated with low Apgar score. CONCLUSION: Both types of malaria cause considerable morbidity in pregnant women. More cases occurred among primigravida but multigravida and later trimester of pregnancy had more severe disease.
INTRODUCTION:Malaria occurring in pregnancy is associated with considerable maternal and perinatal morbidity. In India, the problem is compounded by dual parasitological aetiology of Plasmodiumvivax (P.vivax) and Plasmodium falciparum (P.falciparum). AIM: To compare the outcome of infections by P. vivax and P.falciparum species among pregnant women in a hospital setting. MATERIALS AND METHODS: Pregnant women who tested positive for malaria either by microscopy of peripheral blood smear or ELISA test for double antigen were enrolled in the study. They were followed up till their delivery and discharge from hospital. Demographic, clinical and laboratory data was collected at enrolment, on event of complication and at delivery. Data was analyzed for univariate and multivariate associations. RESULTS: There were 64 pregnant women diagnosed with malaria. A total of 76.6% study subjects had vivax infection rest were infected with p. falciparum. Anaemia (84%) was the commonest complication. A total of 60.9% women had pathological placenta. Preterm delivery, low birth weight and Apgar score <7 were the adverse pregnancy outcomes which were more frequent with falciparum infection. There were three perinatal deaths. Multigravidas were at significantly higher risk for low birth weight and low Apgar score of newborn. Infection in later trimester was associated with low Apgar score. CONCLUSION: Both types of malaria cause considerable morbidity in pregnant women. More cases occurred among primigravida but multigravida and later trimester of pregnancy had more severe disease.
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Authors: Marcus V G Lacerda; Maria P G Mourão; Márcia A A Alexandre; André M Siqueira; Belisa M L Magalhães; Flor E Martinez-Espinosa; Franklin S Santana Filho; Patrícia Brasil; Ana M R S Ventura; Mauro S Tada; Vanja S C D Couto; Antônio R Silva; Rita S U Silva; Maria G C Alecrim Journal: Malar J Date: 2012-01-09 Impact factor: 2.979