| Literature DB >> 28273470 |
Nicole M Chapman1, Hongbo Chi2.
Abstract
T cells promote inflammation in obesity, but how metabolic stress associated with obesity alters T cell responses remains unclear. In this issue of Cell Metabolism,Mauro et al. (2017) demonstrate that saturated fatty acids directly increase effector-memory T cell formation by amplifying T cell antigen-receptor-induced PI3K/Akt signaling.Entities:
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Year: 2017 PMID： 28273470 DOI： 10.1016/j.cmet.2017.02.012
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287