Literature DB >> 28271432

Pharmacotherapy for Weight Management in the VHA.

Todd P Semla1,2, Chris Ruser3,4, Chester B Good5,6,7, Susan Z Yanovski8, Donna Ames9,10, Laurel A Copeland11, Charles Billington12, U Inge Ferguson13, Louis J Aronne14, Thomas A Wadden15, W Timothy Garvey16,17, Caroline M Apovian18, David Atkins19.   

Abstract

Weight management medications (WMM) are underutilized as an adjunct to behavioral and lifestyle interventions. In fiscal years 2014-2015, a total of approximately 2500 veterans-a mere 2% of veterans receiving care from the Veterans Health Administration (VHA)-eligible for a WMM received a prescription for one. A State of the Art Conference on Weight Management workgroup, focused on pharmacotherapy, developed evidence-based recommendations and strategies to foster the appropriate use of WMM in the VHA. The workgroup identified patient, prescriber, and health system barriers to and facilitators for prescribing WMM. Barriers included patient and provider concerns about medication safety and efficacy, limited involvement of primary care, restrictive medication criteria for use (CFU), and skepticism among providers regarding the safety and efficacy of WMM and the perception of obesity as a disease. Potential facilitators for removing barriers included patient and provider education about WMM and the health benefits of weight loss, increased engagement of primary care providers in weight management, relaxation of the CFU, and creation of a system to help patients navigate through weight management treatment options. Several research questions were framed with regard to WMM in general, and specifically to the care of obese veterans. While some of the workgroup's conclusions reflect issues specific to the VHA, many are likely to be applicable to other health organizations.

Entities:  

Keywords:  obesity; pharmaceutical care; veterans

Mesh:

Substances:

Year:  2017        PMID: 28271432      PMCID: PMC5359152          DOI: 10.1007/s11606-016-3949-y

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


  25 in total

1.  Time series analyses of the effect of FDA communications on use of prescription weight loss medications.

Authors:  Jason P Block; Niteesh K Choudhry; Daniel P Carpenter; Michael A Fischer; Troyen A Brennan; Angela Y Tong; Olga S Matlin; William H Shrank
Journal:  Obesity (Silver Spring)       Date:  2013-12-02       Impact factor: 5.002

2.  Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.

Authors:  Frank L Greenway; Ken Fujioka; Raymond A Plodkowski; Sunder Mudaliar; Maria Guttadauria; Janelle Erickson; Dennis D Kim; Eduardo Dunayevich
Journal:  Lancet       Date:  2010-07-29       Impact factor: 79.321

3.  Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study.

Authors:  Patrick M O'Neil; Steven R Smith; Neil J Weissman; Meredith C Fidler; Matilde Sanchez; Jinkun Zhang; Brian Raether; Christen M Anderson; William R Shanahan
Journal:  Obesity (Silver Spring)       Date:  2012-03-16       Impact factor: 5.002

Review 4.  Detecting and Managing Adverse Effects of Antipsychotic Medications: Current State of Play.

Authors:  Donna Ames; Sian M Carr-Lopez; Mary A Gutierrez; Joseph M Pierre; Jennifer A Rosen; Susan Shakib; Lynn M Yudofsky
Journal:  Psychiatr Clin North Am       Date:  2016-03-28

5.  RE-AIM evaluation of the Veterans Health Administration's MOVE! Weight Management Program.

Authors:  Leila C Kahwati; Trang X Lance; Kenneth R Jones; Linda S Kinsinger
Journal:  Transl Behav Med       Date:  2011-12       Impact factor: 3.046

6.  Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial.

Authors:  Thomas A Wadden; John P Foreyt; Gary D Foster; James O Hill; Samuel Klein; Patrick M O'Neil; Michael G Perri; F Xavier Pi-Sunyer; Cheryl L Rock; Janelle S Erickson; Holly N Maier; Dennis D Kim; Eduardo Dunayevich
Journal:  Obesity (Silver Spring)       Date:  2010-06-17       Impact factor: 5.002

7.  Naltrexone extended-release plus bupropion extended-release for treatment of obesity.

Authors:  Susan Z Yanovski; Jack A Yanovski
Journal:  JAMA       Date:  2015 Mar 24-31       Impact factor: 56.272

Review 8.  Long-term drug treatment for obesity: a systematic and clinical review.

Authors:  Susan Z Yanovski; Jack A Yanovski
Journal:  JAMA       Date:  2014-01-01       Impact factor: 56.272

Review 9.  Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis.

Authors:  Rohan Khera; Mohammad Hassan Murad; Apoorva K Chandar; Parambir S Dulai; Zhen Wang; Larry J Prokop; Rohit Loomba; Michael Camilleri; Siddharth Singh
Journal:  JAMA       Date:  2016-06-14       Impact factor: 56.272

10.  A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.

Authors:  Xavier Pi-Sunyer; Arne Astrup; Ken Fujioka; Frank Greenway; Alfredo Halpern; Michel Krempf; David C W Lau; Carel W le Roux; Rafael Violante Ortiz; Christine Bjørn Jensen; John P H Wilding
Journal:  N Engl J Med       Date:  2015-07-02       Impact factor: 91.245

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  4 in total

1.  Patient Characteristics Associated with Receipt of Prescription Weight-Management Medications Among Veterans Participating in MOVE!

Authors:  Dylan D Thomas; Molly E Waring; Omid Ameli; Joel I Reisman; Varsha G Vimalananda
Journal:  Obesity (Silver Spring)       Date:  2019-05-15       Impact factor: 5.002

2.  Obesity Pharmacotherapy is Effective in the Veterans Affairs Patient Population: A Local and Virtual Cohort Study.

Authors:  Jay Pendse; Franco Vallejo-García; Andrew Parziale; Mae Callanan; Craig Tenner; José O Alemán
Journal:  Obesity (Silver Spring)       Date:  2021-02       Impact factor: 5.002

Review 3.  Long-Term Efficacy and Safety of Anti-Obesity Treatment: Where Do We Stand?

Authors:  Young Jin Tak; Sang Yeoup Lee
Journal:  Curr Obes Rep       Date:  2021-01-06

4.  Protocol and short-term results for a feasibility randomized controlled trial of a video intervention for Veterans with obesity: The TOTAL (Teaching Obesity Treatment Options to Adult Learners) pilot study.

Authors:  Luke M Funk; Catherine R Breuer; Manasa Venkatesh; Anna Muraveva; Esra Alagoz; Bret M Hanlon; Susan D Raffa; Corrine I Voils
Journal:  Contemp Clin Trials Commun       Date:  2021-06-29
  4 in total

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