Literature DB >> 28271269

[A 20-year-old woman with ulcerative colitis and acute liver failure].

R Forker1, M Escher2, E F Stange3.   

Abstract

A 20-year-old woman presented with acute exacerbation of ulcerative colitis. After treatment with infliximab, she developed a fulminant liver failure. Under supportive therapy and steroid medication, recovery of symptoms and transaminases occurred. A few case reports about hepatic side effects of anti-TNF-α antibodies in patients with inflammatory bowel disease have been published. These side effects ranged from asymptomatic increase of transaminases to fulminant liver failure necessitating transplantation. The pathomechanism is not fully understood; in some case reports autoimmune phenomena have been described.

Entities:  

Keywords:  Antibodies; Drug-induced liver injury; Hepatitis, autoimmune; Infliximab; Tumor necrosis factor-α

Mesh：

Substances：

Year:  2017        PMID： 28271269     DOI： 10.1007/s00108-017-0205-4

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN： 0020-9554            Impact factor:   0.743


  11 in total

1.  Infliximab exerts no direct hepatotoxic effect on HepG2 cells in vitro.

Authors:  Hilbert S de Vries; Tineke de Heij; Henie M J Roelofs; Rene H M te Morsche; Wilbert H M Peters; Dirk J de Jong
Journal:  Dig Dis Sci       Date:  2012-04-26       Impact factor: 3.199

2.  Drug induced liver injury and its relationship to autoimmune hepatitis.

Authors:  Christina Weiler-Normann; Christoph Schramm
Journal:  J Hepatol       Date:  2011-03-09       Impact factor: 25.083

3.  Infliximab-associated reversible cholestatic liver disease.

Authors:  V V Menghini; A S Arora
Journal:  Mayo Clin Proc       Date:  2001-01       Impact factor: 7.616

4.  A case report: ulcerative colitis, treatment with an antibody against tumor necrosis factor (infliximab), and subsequent liver necrosis.

Authors:  Urpo Kinnunen; Martti Färkkilä; Heikki Mäkisalo
Journal:  J Crohns Colitis       Date:  2012-03-02       Impact factor: 9.071

Review 5.  Liver injury from tumor necrosis factor-α antagonists: analysis of thirty-four cases.

Authors:  Marwan Ghabril; Herbert L Bonkovsky; Clarissa Kum; Tim Davern; Paul H Hayashi; David E Kleiner; Jose Serrano; Jim Rochon; Robert J Fontana; Maurizio Bonacini
Journal:  Clin Gastroenterol Hepatol       Date:  2013-01-17       Impact factor: 11.382

Review 6.  [Drug-induced liver injury with an autoimmune phenotype following anti-TNF Therapy - presentation of cases and review of literature].

Authors:  S Rösner; A Schad; J Kittner; F Rahman; M A Wörns; M Schuchmann; P R Galle; J M Schattenberg
Journal:  Z Gastroenterol       Date:  2014-01-13       Impact factor: 2.000

7.  [Anticytokine therapy].

Authors:  L Naumann; E Feist; G-R Burmester
Journal:  Internist (Berl)       Date:  2013-04       Impact factor: 0.743

8.  Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure.

Authors:  William M Lee; Linda S Hynan; Lorenzo Rossaro; Robert J Fontana; R Todd Stravitz; Anne M Larson; Timothy J Davern; Natalie G Murray; Timothy McCashland; Joan S Reisch; Patricia R Robuck
Journal:  Gastroenterology       Date:  2009-06-12       Impact factor: 22.682

Review 9.  Infliximab-related hepatitis: discussion of a case and review of the literature.

Authors:  Stefano Mancini; Elisa Amorotti; Sarah Vecchio; Maurizio Ponz de Leon; Luca Roncucci
Journal:  Intern Emerg Med       Date:  2010-01-27       Impact factor: 3.397

10.  Liver Injury Secondary to Anti-TNF-Alpha Therapy in Inflammatory Bowel Disease: A Case Series and Review of the Literature.

Authors:  Ravish Parekh; Nirmal Kaur
Journal:  Case Rep Gastrointest Med       Date:  2014-01-19
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  2 in total

Review 1.  Acute Liver Failure from Tumor Necrosis Factor-α Antagonists: Report of Four Cases and Literature Review.

Authors:  Beverley Kok; Erica L W Lester; William M Lee; A James Hanje; R Todd Stravitz; Safwat Girgis; Vaishali Patel; Joshua R Peck; Christopher Esber; Constantine J Karvellas
Journal:  Dig Dis Sci       Date:  2018-03-21       Impact factor: 3.199

Review 2.  Biologic and Checkpoint Inhibitor-Induced Liver Injury: A Systematic Literature Review.

Authors:  Parth Shah; Vinay Sundaram; Einar Björnsson
Journal:  Hepatol Commun       Date:  2020-01-02
  2 in total

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