Literature DB >> 28270963

Optimized sensitivity of Silicon-on-Insulator (SOI) strip waveguide resonator sensor.

Sahba TalebiFard1, Shon Schmidt2, Wei Shi3, WenXuan Wu2, Nicolas A F Jaeger1, Ezra Kwok4, Daniel M Ratner2, Lukas Chrostowski1.   

Abstract

Evanescent field sensors have shown promise for biological sensing applications. In particular, Silicon-on-Insulator (SOI)-nano-photonic based resonator sensors have many advantages for lab-on-chip diagnostics, including high sensitivity for molecular detection and compatibility with CMOS foundries for high volume manufacturing. We have investigated the optimum design parameters within the fabrication constraints of Multi-Project Wafer (MPW) foundries that result in the highest sensitivity for a resonator sensor. We have demonstrated the optimum waveguide thickness needed to achieve the maximum bulk sensitivity with SOI-based resonator sensors to be 165 nm using the quasi-TM guided mode. The closest thickness offered by MPW foundry services is 150 nm. Therefore, resonators with 150 nm thick silicon waveguides were fabricated resulting in sensitivities as high as 270 nm/RIU, whereas a similar resonator sensor with a 220 nm thick waveguide demonstrated sensitivities of approximately 200 nm/RIU.

Entities:  

Keywords:  (140.4780) Optical resonators; (280.1415) Biological sensing and sensors

Year:  2017        PMID: 28270963      PMCID: PMC5330585          DOI: 10.1364/BOE.8.000500

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN: 2156-7085            Impact factor:   3.732


  20 in total

1.  Convergent solutions to binding at a protein-protein interface.

Authors:  W L DeLano; M H Ultsch; A M de Vos; J A Wells
Journal:  Science       Date:  2000-02-18       Impact factor: 47.728

2.  Focusing sub-wavelength grating couplers with low back reflections for rapid prototyping of silicon photonic circuits.

Authors:  Yun Wang; Xu Wang; Jonas Flueckiger; Han Yun; Wei Shi; Richard Bojko; Nicolas A F Jaeger; Lukas Chrostowski
Journal:  Opt Express       Date:  2014-08-25       Impact factor: 3.894

3.  Silicon photonic micro-disk resonators for label-free biosensing.

Authors:  Samantha M Grist; Shon A Schmidt; Jonas Flueckiger; Valentina Donzella; Wei Shi; Sahba Talebi Fard; James T Kirk; Daniel M Ratner; Karen C Cheung; Lukas Chrostowski
Journal:  Opt Express       Date:  2013-04-08       Impact factor: 3.894

4.  Performance of ultra-thin SOI-based resonators for sensing applications.

Authors:  Sahba Talebi Fard; Valentina Donzella; Shon A Schmidt; Jonas Flueckiger; Samantha M Grist; Pouria Talebi Fard; Yichen Wu; Rick J Bojko; Ezra Kwok; Nicolas A F Jaeger; Daniel M Ratner; Lukas Chrostowski
Journal:  Opt Express       Date:  2014-06-16       Impact factor: 3.894

5.  Structural origins of high-affinity biotin binding to streptavidin.

Authors:  P C Weber; D H Ohlendorf; J J Wendoloski; F R Salemme
Journal:  Science       Date:  1989-01-06       Impact factor: 47.728

6.  Characterization of the evanescent field profile and bound mass sensitivity of a label-free silicon photonic microring resonator biosensing platform.

Authors:  Matthew S Luchansky; Adam L Washburn; Teresa A Martin; Muzammil Iqbal; L Cary Gunn; Ryan C Bailey
Journal:  Biosens Bioelectron       Date:  2010-07-12       Impact factor: 10.618

7.  Adsorption and Bioactivity of Protein A on Silicon Surfaces Studied by AFM and XPS.

Authors: 
Journal:  J Colloid Interface Sci       Date:  2001-01-15       Impact factor: 8.128

8.  Quantitative, label-free detection of five protein biomarkers using multiplexed arrays of silicon photonic microring resonators.

Authors:  Adam L Washburn; Matthew S Luchansky; Adrienne L Bowman; Ryan C Bailey
Journal:  Anal Chem       Date:  2010-01-01       Impact factor: 6.986

9.  The density and refractive index of adsorbing protein layers.

Authors:  Janos Vörös
Journal:  Biophys J       Date:  2004-07       Impact factor: 4.033

10.  Label-free quantitation of a cancer biomarker in complex media using silicon photonic microring resonators.

Authors:  Adam L Washburn; L Cary Gunn; Ryan C Bailey
Journal:  Anal Chem       Date:  2009-11-15       Impact factor: 6.986

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  7 in total

1.  Multi-slot photonic crystal cavities for high-sensitivity refractive index sensing.

Authors:  Peipeng Xu; Jiajiu Zheng; Jun Zhou; Yueyang Chen; Chen Zou; Arka Majumdar
Journal:  Opt Express       Date:  2019-02-04       Impact factor: 3.894

2.  Post-fabrication tuning of microring resonators using 3D-printed microfluidics.

Authors:  Kevin Larson; Alec Hammond; Christian Carver; Derek Anderson; Matthew Viglione; Mawla Boaks; Greg Nordin; Ryan M Camacho
Journal:  Opt Lett       Date:  2021-09-15       Impact factor: 3.560

Review 3.  Surface Plasmon Resonance (SPR) Spectroscopy and Photonic Integrated Circuit (PIC) Biosensors: A Comparative Review.

Authors:  Patrick Steglich; Giulia Lecci; Andreas Mai
Journal:  Sensors (Basel)       Date:  2022-04-09       Impact factor: 3.847

4.  A Tellurium Oxide Microcavity Resonator Sensor Integrated On-Chip with a Silicon Waveguide.

Authors:  Henry C Frankis; Daniel Su; Dawson B Bonneville; Jonathan D B Bradley
Journal:  Sensors (Basel)       Date:  2018-11-21       Impact factor: 3.576

5.  Hollow-Core Fiber-Based Biosensor: A Platform for Lab-in-Fiber Optical Biosensors for DNA Detection.

Authors:  Foroogh Khozeymeh; Federico Melli; Sabrina Capodaglio; Roberto Corradini; Fetah Benabid; Luca Vincetti; Annamaria Cucinotta
Journal:  Sensors (Basel)       Date:  2022-07-08       Impact factor: 3.847

Review 6.  Silicon Photonic Biosensors Using Label-Free Detection.

Authors:  Enxiao Luan; Hossam Shoman; Daniel M Ratner; Karen C Cheung; Lukas Chrostowski
Journal:  Sensors (Basel)       Date:  2018-10-18       Impact factor: 3.576

7.  Hyperchromatic structural color for perceptually enhanced sensing by the naked eye.

Authors:  Tahmid H Talukdar; Bria McCoy; Sarah K Timmins; Taufiquar Khan; Judson D Ryckman
Journal:  Proc Natl Acad Sci U S A       Date:  2020-11-16       Impact factor: 11.205

  7 in total

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