Literature DB >> 28267566

Aging and efficiency in living systems: Complexity, adaptation and self-organization.

Atanu Chatterjee1, Georgi Georgiev2, Germano Iannacchione3.   

Abstract

Living systems are open, out-of-equilibrium thermodynamic entities, that maintain order by locally reducing their entropy. Aging is a process by which these systems gradually lose their ability to maintain their out-of-equilibrium state, as measured by their free-energy rate density, and hence, their order. Thus, the process of aging reduces the efficiency of those systems, making them fragile and less adaptive to the environmental fluctuations, gradually driving them towards the state of thermodynamic equilibrium. In this paper, we discuss the various metrics that can be used to understand the process of aging from a complexity science perspective. Among all the metrics that we propose, action efficiency, is observed to be of key interest as it can be used to quantify order and self-organization in any physical system. Based upon our arguments, we present the dependency of other metrics on the action efficiency of a system, and also argue as to how each of the metrics, influences all the other system variables. In order to support our claims, we draw parallels between technological progress and biological growth. Such parallels are used to support the universal applicability of the metrics and the methodology presented in this paper. Therefore, the results and the arguments presented in this paper throw light on the finer nuances of the science of aging.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Action; Adaptation; Aging; Complexity; Efficiency; Entropy; Self-organization

Mesh:

Year:  2017        PMID: 28267566     DOI: 10.1016/j.mad.2017.02.009

Source DB:  PubMed          Journal:  Mech Ageing Dev        ISSN: 0047-6374            Impact factor:   5.432


  4 in total

Review 1.  The Cognitive Lens: a primer on conceptual tools for analysing information processing in developmental and regenerative morphogenesis.

Authors:  Santosh Manicka; Michael Levin
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2019-06-10       Impact factor: 6.237

2.  Coexisting Ordered States, Local Equilibrium-like Domains, and Broken Ergodicity in a Non-turbulent Rayleigh-Bénard Convection at Steady-state.

Authors:  Atanu Chatterjee; Yash Yadati; Nicholas Mears; Germano Iannacchione
Journal:  Sci Rep       Date:  2019-07-23       Impact factor: 4.379

3.  An Overview of Emergent Order in Far-from-Equilibrium Driven Systems: From Kuramoto Oscillators to Rayleigh-Bénard Convection.

Authors:  Atanu Chatterjee; Nicholas Mears; Yash Yadati; Germano S Iannacchione
Journal:  Entropy (Basel)       Date:  2020-05-17       Impact factor: 2.524

4.  Mesenchymal stromal cell aging impairs the self-organizing capacity of lung alveolar epithelial stem cells.

Authors:  Diptiman Chanda; Mohammad Rehan; Samuel R Smith; Kevin G Dsouza; Yong Wang; Karen Bernard; Deepali Kurundkar; Vinayak Memula; Kyoko Kojima; James A Mobley; Gloria A Benavides; Victor Darley-Usmar; Young-iL Kim; Jaroslaw W Zmijewski; Jessy S Deshane; Stijn De Langhe; Victor J Thannickal
Journal:  Elife       Date:  2021-09-16       Impact factor: 8.713

  4 in total

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