Literature DB >> 28265684

[Leukopenia with unclear fever].

S Mayer1, T Kündiger2, H Schrader2.   

Abstract

We report on a 77-year-old male patient with neutropenic fever as a result of a newly diagnosed agranulocytosis. The patient was taking metamizole, which is a well known cause of agranulocytosis. The diagnosis of metamizole-induced agranulocytosis as an underestimated side-effect of metamizole could be confirmed by a bone marrow biopsy. The bone marrow and the blood count recovered completely after stopping the therapy with metamizole and administration of granulocyte colony-stimulating factor (G-CSF).

Entities:  

Keywords:  Agranulocytosis; Biopsy, bone marrow; Dipyrone, adverse effects; Febrile neutropenia; Granulocyte colony-stimulating factor

Mesh:

Substances:

Year:  2017        PMID: 28265684     DOI: 10.1007/s00108-017-0207-2

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  7 in total

1.  Non-chemotherapy drug-induced agranulocytosis in a tertiary hospital.

Authors:  R Navarro-Martínez; E Chover-Sierra; O Cauli
Journal:  Hum Exp Toxicol       Date:  2015-04-05       Impact factor: 2.903

2.  Agranulocytosis associated with dipyrone (metamizol).

Authors:  Luisa Ibáñez; Xavier Vidal; Elena Ballarín; Joan-Ramon Laporte
Journal:  Eur J Clin Pharmacol       Date:  2004-12-03       Impact factor: 2.953

3.  Metamizole (dipyrone)-associated agranulocytosis. An analysis of German spontaneous reports 1990-2012.

Authors:  Thomas Stammschulte; Wolf-Dieter Ludwig; Bernd Mühlbauer; Elisabeth Bronder; Ursula Gundert-Remy
Journal:  Eur J Clin Pharmacol       Date:  2015-07-15       Impact factor: 2.953

Review 4.  Systematic review: agranulocytosis induced by nonchemotherapy drugs.

Authors:  Frank Andersohn; Christine Konzen; Edeltraut Garbe
Journal:  Ann Intern Med       Date:  2007-05-01       Impact factor: 25.391

5.  Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study.

Authors: 
Journal:  JAMA       Date:  1986-10-03       Impact factor: 56.272

6.  Agranulocytosis and other blood dyscrasias associated with dipyrone (metamizole).

Authors:  Karin Hedenmalm; Olav Spigset
Journal:  Eur J Clin Pharmacol       Date:  2002-06-06       Impact factor: 2.953

Review 7.  Idiosyncratic drug-induced agranulocytosis or acute neutropenia.

Authors:  Emmanuel Andrès; Frédéric Maloisel
Journal:  Curr Opin Hematol       Date:  2008-01       Impact factor: 3.284

  7 in total

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