Literature DB >> 28263857

Organ Donation, an Unexpected Benefit of Aggressive Resuscitation of Trauma Patients Presenting Dead on Arrival.

Abdul Q Alarhayem1, Stephen M Cohn2, Mark T Muir3, John G Myers3, James Fuqua3, Brian J Eastridge3.   

Abstract

BACKGROUND: We sought to determine whether aggressive resuscitation in trauma patients presenting without vital signs, or "dead on arrival," was futile. We also sought to determine whether organ donation was an unexpected benefit of aggressive resuscitation. STUDY
DESIGN: We conducted a review of adults presenting to our Level I trauma center with no signs of life (pulse = 0 beats/min; systolic blood pressure = 0 mmHg; and no evidence of neurologic activity, Glasgow Coma Scale score = 3). Primary end point was survival to hospital discharge or major organ donation (ie heart, lung, kidney, liver, or pancreas were harvested). We compared our survival rates with those of the National Trauma Data Bank in 2012. Patient demographics, emergency department vital signs, and outcomes were analyzed.
RESULTS: Three hundred and forty patients presented with no signs of life to our emergency department after injury (median Injury Severity Score = 40). There were 7 survivors to discharge, but only 5 (1.5%) were functionally independent (4 were victims of penetrating trauma). Of the 333 nonsurvivors, 12 patients (3.6%) donated major organs (16 kidneys, 2 hearts, 4 livers, and 2 lungs). An analysis of the National Trauma Data Bank yielded a comparable survival rate for those presenting dead on arrival, with an overall survival rate of 1.8% (100 of 5,384); 2.3% for blunt trauma and 1.4% for penetrating trauma.
CONCLUSIONS: Trauma patients presenting dead on arrival rarely (1.5%) achieve functional independence. However, organ donation appears to be an under-recognized outcomes benefit (3.6%) of the resuscitation of injury victims arriving without vital signs. Published by Elsevier Inc.

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Year:  2017        PMID: 28263857     DOI: 10.1016/j.jamcollsurg.2017.02.012

Source DB:  PubMed          Journal:  J Am Coll Surg        ISSN: 1072-7515            Impact factor:   6.113


  2 in total

1.  Centralization of Major Trauma Influences Liver Availability for Transplantation in Northern Italy: Lesson Learned from COVID-19 Pandemic.

Authors:  Michele Altomare; Andrea Chierici; Francesco Virdis; Andrea Spota; Stefano Piero Bernardo Cioffi; Shir Sara Bekhor; Luca Del Prete; Elisa Reitano; Marco Sacchi; Federico Ambrogi; Osvaldo Chiara; Stefania Cimbanassi
Journal:  J Clin Med       Date:  2022-06-24       Impact factor: 4.964

2.  Outcomes and indications for emergency thoracotomy after adoption of a more liberal policy in a western European level 1 trauma centre: 8-year experience.

Authors:  Edoardo Segalini; Luca Di Donato; Arianna Birindelli; Alice Piccinini; Alberto Casati; Carlo Coniglio; Salomone Di Saverio; Gregorio Tugnoli
Journal:  Updates Surg       Date:  2018-12-26
  2 in total

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