Literature DB >> 2826305

Spin trapping of oxygen and carbon-centered free radicals in ischemic canine myocardium.

C M Arroyo1, J H Kramer, R H Leiboff, G W Mergner, B F Dickens, W B Weglicki.   

Abstract

Oxygen free radical injury has been postulated to occur during myocardial ischemia. We have used Electron Spin Resonance and Spin Trapping techniques to directly demonstrate the production of carbon-centered (R.) and oxygen-centered lipid radical (RO.) in ischemic canine heart. In addition, venous effluent from the ischemic region showed that conjugated dienes (lipid peroxidation products) increased with ischemic duration. Our results suggest that the formation of the oxygen-centered and carbon-centered lipid radical species during ischemia are a consequence of oxy-radical peroxidation of myocardial membrane lipids.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 2826305     DOI： 10.1016/s0891-5849(87)80037-0

Source DB:  PubMed          Journal:  Free Radic Biol Med        ISSN： 0891-5849            Impact factor:   7.376


  18 in total

1.  Oxygen radicals generated at reflow induce peroxidation of membrane lipids in reperfused hearts.

Authors:  G Ambrosio; J T Flaherty; C Duilio; I Tritto; G Santoro; P P Elia; M Condorelli; M Chiariello
Journal:  J Clin Invest       Date:  1991-06       Impact factor: 14.808

2.  Radical adducts of nitrosobenzene and 2-methyl-2-nitrosopropane with 12,13-epoxylinoleic acid radical, 12,13-epoxylinolenic acid radical and 14,15-epoxyarachidonic acid radical. Identification by h.p.l.c.-e.p.r. and liquid chromatography-thermospray-m.s.

Authors:  H Iwahashi; C E Parker; R P Mason; K B Tomer
Journal:  Biochem J       Date:  1991-06-01       Impact factor: 3.857

3.  Radicals and molecular products from the gas-phase pyrolysis of lignin model compounds. Cinnamyl alcohol.

Authors:  Lavrent Khachatryan; Meng-Xia Xu; Ang-Jian Wu; Mikhail Pechagin; Rubik Asatryan
Journal:  J Anal Appl Pyrolysis       Date:  2016-07-09       Impact factor: 5.541

4.  Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion.

Authors:  G Martinez; M L Carnazza; C D Giacomo; V Sorrenti; R Castana; G Pennisi; J R Perez-Polo; A Vanella
Journal:  Neurochem Res       Date:  1996-06       Impact factor: 3.996

5.  Free radical scavenger depletion in post-ischemic reperfusion brain damage.

Authors:  A Vanella; C Di Giacomo; V Sorrenti; A Russo; C Castorina; A Campisi; M Renis; J R Perez-Polo
Journal:  Neurochem Res       Date:  1993-12       Impact factor: 3.996

6.  Does the antiarrhythmic effect of DMPO originate from its oxygen radical trapping property or the structure of the molecule itself?

Authors:  A Tosaki; R F Haseloff; A Hellegouarch; K Schoenheit; V V Martin; D K Das; I E Blasig
Journal:  Basic Res Cardiol       Date:  1992 Nov-Dec       Impact factor: 17.165

7.  Lysosomal lipolytic enzymes, lipid peroxidation, and injury.

Authors:  B F Dickens; I T Mak; W B Weglicki
Journal:  Mol Cell Biochem       Date:  1988 Jul-Aug       Impact factor: 3.396

8.  Demonstration of free radical generation in the "stunned" myocardium in the conscious dog and identification of major differences between conscious and open-chest dogs.

Authors:  X Y Li; P B McCay; M Zughaib; M O Jeroudi; J F Triana; R Bolli
Journal:  J Clin Invest       Date:  1993-08       Impact factor: 14.808

9.  The formation of free radicals by cardiac myocytes under oxidative stress and the effects of electron-donating drugs.

Authors:  J J Turner; C A Rice-Evans; M J Davies; E S Newman
Journal:  Biochem J       Date:  1991-08-01       Impact factor: 3.857

10.  Essential fatty acids alter the activity of manganese-superoxide dismutase in rat heart.

Authors:  A C Phylactos; L S Harbige; M A Crawford
Journal:  Lipids       Date:  1994-02       Impact factor: 1.880
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.