OBJECTIVES: Hypertrophic cardiomyopathy (HCM) is a life-threatening genetic cardiovascular disease that often goes undetected in young athletes. Neither history nor physical examination are reliable to identify those at risk. The objective of this study is to determine whether minimally trained medical student volunteers can use ultrasound to screen for HCM. METHODS: This was a prospective enrollment of young athletes performed at 12 area high schools and three area colleges, between May 2012 and August 2013. All participants underwent point-of-care ultrasound performed screening for HCM by trained medical students and reviewed by a pediatric cardiologist. An interventricular septum to left ventricular posterior wall ratio greater than 1.25 was considered to be abnormal (positive screen). RESULTS: A total of 2332 participants were enrolled. There were 137 (5.8%) with a positive screening for HCM, of which 7 (5.1%) were confirmed to have HCM by a pediatric cardiologist. In a small cohort with positive screen for HCM, there was a 100% sensitivity (95% confidence interval, 59.04 to 100%) and 4.86% (95% confidence interval, 1.98 to 9.76%) positive predictive value of for having HCM. CONCLUSIONS: Volunteer medical students, using point-of-care ultrasound, were able to effectively screen for HCM in young athletes.
OBJECTIVES:Hypertrophic cardiomyopathy (HCM) is a life-threatening genetic cardiovascular disease that often goes undetected in young athletes. Neither history nor physical examination are reliable to identify those at risk. The objective of this study is to determine whether minimally trained medical student volunteers can use ultrasound to screen for HCM. METHODS: This was a prospective enrollment of young athletes performed at 12 area high schools and three area colleges, between May 2012 and August 2013. All participants underwent point-of-care ultrasound performed screening for HCM by trained medical students and reviewed by a pediatric cardiologist. An interventricular septum to left ventricular posterior wall ratio greater than 1.25 was considered to be abnormal (positive screen). RESULTS: A total of 2332 participants were enrolled. There were 137 (5.8%) with a positive screening for HCM, of which 7 (5.1%) were confirmed to have HCM by a pediatric cardiologist. In a small cohort with positive screen for HCM, there was a 100% sensitivity (95% confidence interval, 59.04 to 100%) and 4.86% (95% confidence interval, 1.98 to 9.76%) positive predictive value of for having HCM. CONCLUSIONS: Volunteer medical students, using point-of-care ultrasound, were able to effectively screen for HCM in young athletes.
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Authors: Richard A Hoppmann; Jeanette Mladenovic; Lawrence Melniker; Radu Badea; Michael Blaivas; Miguel Montorfano; Alfred Abuhamad; Vicki Noble; Arif Hussain; Gregor Prosen; Tomás Villen; Gabriele Via; Ramon Nogue; Craig Goodmurphy; Marcus Bastos; G Stephen Nace; Giovanni Volpicelli; Richard J Wakefield; Steve Wilson; Anjali Bhagra; Jongyeol Kim; David Bahner; Chris Fox; Ruth Riley; Peter Steinmetz; Bret P Nelson; John Pellerito; Levon N Nazarian; L Britt Wilson; Irene W Y Ma; David Amponsah; Keith R Barron; Renee K Dversdal; Mike Wagner; Anthony J Dean; David Tierney; James W Tsung; Paula Nocera; José Pazeli; Rachel Liu; Susanna Price; Luca Neri; Barbara Piccirillo; Adi Osman; Vaughan Lee; Nitha Naqvi; Tomislav Petrovic; Paul Bornemann; Maxime Valois; Jean-Francoise Lanctot; Robert Haddad; Deepak Govil; Laura A Hurtado; Vi Am Dinh; Robert M DePhilip; Beatrice Hoffmann; Resa E Lewiss; Nayana A Parange; Akira Nishisaki; Stephanie J Doniger; Paul Dallas; Kevin Bergman; J Oscar Barahona; Ximena Wortsman; R Stephen Smith; Craig A Sisson; James Palma; Mike Mallin; Liju Ahmed; Hassan Mustafa Journal: Ultrasound J Date: 2022-07-27