Alana Zanetti-Yabur1, Amanda Rizzo2, Nicole Hayde3, Anthony C Watkins4, Juan P Rocca5, Jay A Graham5. 1. Montefiore - Einstein Center for Transplantation, Montefiore Medical Center, Bronx, NY, USA. Electronic address: alana.zanetti-yabur@einstein.yu.edu. 2. Albert Einstein College of Medicine, Bronx, NY, USA. 3. Division of Pediatric Nephrology, Montefiore Medical Center, Bronx, NY, USA. 4. New York-Presbyterian/Weill Cornell Medical Center, New York, NY, USA. 5. Montefiore - Einstein Center for Transplantation, Montefiore Medical Center, Bronx, NY, USA.
Abstract
BACKGROUND: Medication non-adherence in transplant patients is a grave problem that results in increased rejection episodes, graft loss and significant morbidity. METHODS: The efficacy of users and non-users of a mobile phone application (mobile app) in promoting medication adherence was investigated. The Beliefs about Medicine Questionnaire (BMQ) and Morisky Medication Adherence Scale (MMAS-8) were used in these cohorts to assess the predilection for poor adherence. Serum tacrolimus, creatinine levels, and rejection episodes were also recorded. Lastly, the patients were tested on their recall of their immunosuppression. RESULTS: Overall, patients had extremely negative beliefs about medication reflected in their tendency toward higher predicted rates of non-adherence. Interestingly, though not significant, app users had higher rates of medication recollection. CONCLUSIONS: The high-risk nature of this population demands efforts to abrogate non-adherence. Caregivers are charged with the responsibility to offer patients a feasible option to safeguard treatment compliance. Mobile apps are a potentially powerful tool, which can be used to decrease non-adherence.
BACKGROUND: Medication non-adherence in transplant patients is a grave problem that results in increased rejection episodes, graft loss and significant morbidity. METHODS: The efficacy of users and non-users of a mobile phone application (mobile app) in promoting medication adherence was investigated. The Beliefs about Medicine Questionnaire (BMQ) and Morisky Medication Adherence Scale (MMAS-8) were used in these cohorts to assess the predilection for poor adherence. Serum tacrolimus, creatinine levels, and rejection episodes were also recorded. Lastly, the patients were tested on their recall of their immunosuppression. RESULTS: Overall, patients had extremely negative beliefs about medication reflected in their tendency toward higher predicted rates of non-adherence. Interestingly, though not significant, app users had higher rates of medication recollection. CONCLUSIONS: The high-risk nature of this population demands efforts to abrogate non-adherence. Caregivers are charged with the responsibility to offer patients a feasible option to safeguard treatment compliance. Mobile apps are a potentially powerful tool, which can be used to decrease non-adherence.
Authors: Videha Sharma; Alex Shaw; Marcus Lowe; Angela Summers; David van Dellen; Titus Augustine Journal: Clin Med (Lond) Date: 2020-05-25 Impact factor: 2.659
Authors: Haley M Gonzales; James N Fleming; Mulugeta Gebregziabher; Maria Aurora Posadas-Salas; Zemin Su; John W McGillicuddy; David J Taber Journal: Clin J Am Soc Nephrol Date: 2021-04-30 Impact factor: 8.237
Authors: Daniela P Ladner; Michael S Wolf; Esther S Yoon; Scott Hur; Laura M Curtis; Aiden H Wynia; Pauline Zheng; Sumi S Nair; Stacy C Bailey; Marina Serper; Peter P Reese Journal: JMIR Form Res Date: 2022-05-05
Authors: Anne-Grete Märtson; Martijn Bakker; Hans Blokzijl; Erik A M Verschuuren; Stefan P Berger; Lambert F R Span; Tjip S van der Werf; Jan-Willem C Alffenaar Journal: BMJ Open Date: 2020-01-07 Impact factor: 2.692