| Literature DB >> 28256122 |
Hai-Yan Tian1, Li-Jun Ruan1, Tong Yu1, Qing-Fei Zheng2, Nan-Hao Chen3, Rui-Bo Wu3, Xiao-Qi Zhang1, Lei Wang1, Ren-Wang Jiang1, Wen-Cai Ye1.
Abstract
Bufospirostenin A (1) and bufogargarizin C (2), two novel steroids with rearranged A/B rings, were isolated from the toad Bufo bufo gargarizans. Compound 1 represents the first spirostanol found in animals. Compound 2 is an unusual bufadienolide with a cycloheptatriene B ring. Their structures were elucidated by spectroscopic analysis, single crystal X-ray diffraction analysis, and computational calculations.Entities:
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Year: 2017 PMID： 28256122 DOI： 10.1021/acs.jnatprod.6b01018
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050