Imane El Sanharawi1, Loukia Tzarouchi1, Liesbeth Cardoen1,2, Laetitia Martinerie2,3,4, Juliane Leger2,3,4, Jean-Claude Carel2,3,4, Monique Elmaleh-Berges1,3, Marianne Alison5,6,7. 1. Service de Radiologie Pédiatrique, Hôpital Robert Debré, APHP, 48 boulevard Sérurier, 75019, Paris, France. 2. Université Paris Diderot, Paris, France. 3. Inserm U1141, DHU PROTECT, Paris, France. 4. Service d'Endocrinologie Pédiatrique, Hôpital Robert Debré, APHP, Paris, France. 5. Service de Radiologie Pédiatrique, Hôpital Robert Debré, APHP, 48 boulevard Sérurier, 75019, Paris, France. marianne.alison@aphp.fr. 6. Université Paris Diderot, Paris, France. marianne.alison@aphp.fr. 7. Inserm U1141, DHU PROTECT, Paris, France. marianne.alison@aphp.fr.
Abstract
BACKGROUND: In anterior pituitary deficiency, patients with non visible pituitary stalk have more often multiple deficiencies and persistent deficiency than patients with visible pituitary stalk. OBJECTIVE: To compare the diagnostic value of a high-resolution heavily T2-weighted sequence to 1.5-mm-thick unenhanced and contrast-enhanced sagittal T1-weighted sequences to assess the presence of the pituitary stalk in children with ectopic posterior pituitary gland. MATERIALS AND METHODS: We retrospectively evaluated the MRI data of 14 children diagnosed with ectopic posterior pituitary gland between 2010 and 2014. We evaluated the presence of a pituitary stalk using a sagittal high-resolution heavily T2-weighted sequence and a 1.5-mm sagittal T1-weighted turbo spin-echo sequence before and after contrast medium administration. RESULTS: A pituitary stalk was present on at least one of the sequences in 10 of the 14 children (71%). T2-weighted sequence depicted the pituitary stalk in all 10 children, whereas the 1.5-mm-thick T1-weighted sequence depicted 2/10 (20%) before contrast injection and 8/10 (80%) after contrast injection (P=0.007). CONCLUSION: Compared with 1.5-mm-thick contrast-enhanced T1-weighted sequences, high-resolution heavily T2-weighted sequence demonstrates better sensitivity in detecting the pituitary stalk in children with ectopic posterior pituitary gland, suggesting that contrast injection is unnecessary to assess the presence of a pituitary stalk in this setting.
BACKGROUND: In anterior pituitary deficiency, patients with non visible pituitary stalk have more often multiple deficiencies and persistent deficiency than patients with visible pituitary stalk. OBJECTIVE: To compare the diagnostic value of a high-resolution heavily T2-weighted sequence to 1.5-mm-thick unenhanced and contrast-enhanced sagittal T1-weighted sequences to assess the presence of the pituitary stalk in children with ectopic posterior pituitary gland. MATERIALS AND METHODS: We retrospectively evaluated the MRI data of 14 children diagnosed with ectopic posterior pituitary gland between 2010 and 2014. We evaluated the presence of a pituitary stalk using a sagittal high-resolution heavily T2-weighted sequence and a 1.5-mm sagittal T1-weighted turbo spin-echo sequence before and after contrast medium administration. RESULTS: A pituitary stalk was present on at least one of the sequences in 10 of the 14 children (71%). T2-weighted sequence depicted the pituitary stalk in all 10 children, whereas the 1.5-mm-thick T1-weighted sequence depicted 2/10 (20%) before contrast injection and 8/10 (80%) after contrast injection (P=0.007). CONCLUSION: Compared with 1.5-mm-thick contrast-enhanced T1-weighted sequences, high-resolution heavily T2-weighted sequence demonstrates better sensitivity in detecting the pituitary stalk in children with ectopic posterior pituitary gland, suggesting that contrast injection is unnecessary to assess the presence of a pituitary stalk in this setting.
Authors: Y Masuda; T Yamamoto; H Akutsu; M Shiigai; T Masumoto; E Ishikawa; M Matsuda; A Matsumura Journal: AJNR Am J Neuroradiol Date: 2014-10-09 Impact factor: 3.825
Authors: Marina Ybarra; Rawan Hafiz; Marie-Eve Robinson; Julia Elisabeth von Oettingen; Helen Bui; Christine Saint-Martin Journal: Pediatr Radiol Date: 2019-08-30