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Literature DB >> 2825194

Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes.

M C Carroll¹, P Katzman, E M Alicot, B H Koller, D E Geraghty, H T Orr, J L Strominger, T Spies.

Abstract

The tumor necrosis factor (TNF) alpha and beta gene pair has been linked in the human major histocompatibility complex to HLA-B, HLA-C, and, tentatively, HLA-E and HLA-A on one side and to the class III complement/steroid 21-hydroxylase gene cluster on the other by pulsed-field gel electrophoresis. The TNF genes are located 200 kilobases (kb) centromeric of HLA-B and about 350 kb telomeric of the class III cluster. Together with previous data on the linkage and structures of the class II and class III regions, a restriction map of the entire human major histocompatibility complex of about 3500 kb has been prepared.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1987 PMID： 2825194 PMCID： PMC299579 DOI： 10.1073/pnas.84.23.8535

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

32 in total

1. Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors: E M Southern
Journal: J Mol Biol Date: 1975-11-05 Impact factor: 5.469

2. Isolation and partial nucleotide sequence of a cDNA clone for human histocompatibility antigen HLA-B by use of an oligodeoxynucleotide primer.

Authors: A K Sood; D Pereira; S M Weissman
Journal: Proc Natl Acad Sci U S A Date: 1981-01 Impact factor: 11.205

3. New techniques for purifying large DNAs and studying their properties and packaging.

Authors: D C Schwartz; W Saffran; J Welsh; R Haas; M Goldenberg; C R Cantor
Journal: Cold Spring Harb Symp Quant Biol Date: 1983

Review 4. Report of the Committee on the Genetic Constitution of Chromosome 6.

Authors: E B Robson; L U Lamm
Journal: Cytogenet Cell Genet Date: 1984

5. Isolation of cDNA clones encoding HLA-DR alpha chains.

Authors: C T Wake; E O Long; M Strubin; N Gross; R Accolla; S Carrel; B Mach
Journal: Proc Natl Acad Sci U S A Date: 1982-11 Impact factor: 11.205

6. A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.

Authors: M C Carroll; R D Campbell; D R Bentley; R R Porter
Journal: Nature Date: 1984 Jan 19-25 Impact factor: 49.962

7. Mouse lymphotoxin and tumor necrosis factor: structural analysis of the cloned genes, physical linkage, and chromosomal position.

Authors: S M Gardner; B A Mock; J Hilgers; K E Huppi; W D Roeder
Journal: J Immunol Date: 1987-07-15 Impact factor: 5.422

8. The structural basis of the multiple forms of human complement component C4.

Authors: K T Belt; M C Carroll; R R Porter
Journal: Cell Date: 1984-04 Impact factor: 41.582

9. Class I-like HLA genes map telomeric to the HLA-A2 locus in human cells.

Authors: H T Orr; R DeMars
Journal: Nature Date: 1983-04-07 Impact factor: 49.962

10. Complete sequence of an HLA-dR beta chain deduced from a cDNA clone and identification of multiple non-allelic DR beta chain genes.

Authors: E O Long; C T Wake; J Gorski; B Mach
Journal: EMBO J Date: 1983 Impact factor: 11.598

93 in total

1. Association of a lymphotoxin alpha gene polymorphism and atopy in Italian families.

Authors: E Trabetti; C Patuzzo; G Malerba; R Galavotti; L C Martinati; A L Boner; P F Pignatti
Journal: J Med Genet Date: 1999-04 Impact factor: 6.318

Review 2. Comparative map for mice and humans.

Authors: J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal: Mamm Genome Date: 1992 Impact factor: 2.957

Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes.

1. Detection of specific sequences among DNA fragments separated by gel electrophoresis.

2. Isolation and partial nucleotide sequence of a cDNA clone for human histocompatibility antigen HLA-B by use of an oligodeoxynucleotide primer.

3. New techniques for purifying large DNAs and studying their properties and packaging.

Review 4. Report of the Committee on the Genetic Constitution of Chromosome 6.

5. Isolation of cDNA clones encoding HLA-DR alpha chains.

6. A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.

7. Mouse lymphotoxin and tumor necrosis factor: structural analysis of the cloned genes, physical linkage, and chromosomal position.

8. The structural basis of the multiple forms of human complement component C4.

9. Class I-like HLA genes map telomeric to the HLA-A2 locus in human cells.

10. Complete sequence of an HLA-dR beta chain deduced from a cDNA clone and identification of multiple non-allelic DR beta chain genes.

1. Association of a lymphotoxin alpha gene polymorphism and atopy in Italian families.

Review 2. Comparative map for mice and humans.

3. A unique recombination event resulting in a C4AQ0,C4BQ0 double null haplotype.

4. A continuous restriction map from HLA-E to HLA-F. Structural comparison between different HLA-A haplotypes.

5. Physical mapping of the MHC and grc by pulse field electrophoresis.

6. Molecular analysis of the human MHC class I region using yeast artificial chromosome clones.

Review 7. HLA non-A,B,C class I genes: their structure and expression.

8. Isolation and characterization of yeast artificial chromosome clones linking the HLA-B and HLA-C loci.

Review 9. Transcriptional regulation of HLA class-II genes.

Review 10. Cytokine polymorphisms in silicosis and other pneumoconioses.