Literature DB >> 2825169

Selective elimination of mRNAs in vivo: complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity.

P Dash1, I Lotan, M Knapp, E R Kandel, P Goelet.   

Abstract

Oligodeoxynucleotides lead to translation arrest of complementary mRNAs in the wheat germ translation system by a degradation of the mRNA. In an attempt to develop an effective reverse genetic approach in vivo, we demonstrate that injection of short (15- to 30-nucleotide) oligonucleotides into Xenopus oocytes leads to complete degradation of both injected and endogenous mRNAs by means of an RNase H-like activity.

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Year:  1987        PMID： 2825169      PMCID： PMC299442          DOI： 10.1073/pnas.84.22.7896

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  26 in total

1.  Antisense RNA injections in fertilized frog eggs reveal an RNA duplex unwinding activity.

Authors:  M R Rebagliati; D A Melton
Journal:  Cell       Date:  1987-02-27       Impact factor: 41.582

2.  Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Authors:  A J Berk; P A Sharp
Journal:  Cell       Date:  1977-11       Impact factor: 41.582

3.  Production of phenocopies by Krüppel antisense RNA injection into Drosophila embryos.

Authors:  U B Rosenberg; A Preiss; E Seifert; H Jäckle; D C Knipple
Journal:  Nature       Date:  1985 Feb 21-27       Impact factor: 49.962

4.  The use of single-stranded DNA and RNase H to promote quantitative 'hybrid arrest of translation' of mRNA/DNA hybrids in reticulocyte lysate cell-free translations.

Authors:  J Minshull; T Hunt
Journal:  Nucleic Acids Res       Date:  1986-08-26       Impact factor: 16.971

5.  Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

Authors:  P S Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

6.  A simple and very efficient method for generating cDNA libraries.

Authors:  U Gubler; B J Hoffman
Journal:  Gene       Date:  1983-11       Impact factor: 3.688

7.  Isolation and nucleotide sequence of the rabbit globin gene cluster psi zeta-alpha 1-psi alpha. Absence of a pair of alpha-globin genes evolving in concert.

Authors:  J F Cheng; L Raid; R C Hardison
Journal:  J Biol Chem       Date:  1986-01-15       Impact factor: 5.157

8.  Transcription unit of the rabbit beta 1 globin gene.

Authors:  M L Rohrbaugh; J E Johnson; M D James; R C Hardison
Journal:  Mol Cell Biol       Date:  1985-01       Impact factor: 4.272

9.  Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA.

Authors:  P C Zamecnik; J Goodchild; Y Taguchi; P S Sarin
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

10.  Stable reduction of thymidine kinase activity in cells expressing high levels of anti-sense RNA.

Authors:  S K Kim; B J Wold
Journal:  Cell       Date:  1985-08       Impact factor: 41.582
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  55 in total

Review 1.  Peptide nucleic acids: versatile tools for gene therapy strategies.

Authors:  D A Dean
Journal:  Adv Drug Deliv Rev       Date:  2000-11-15       Impact factor: 15.470

2.  Post-transcriptional silencing of Notch2 mRNA in chronic lymphocytic [corrected] leukemic cells of B-CLL patients.

Authors:  Kaneez Fatima; Rehan Zafar Paracha; Ishtiaq Qadri
Journal:  Mol Biol Rep       Date:  2011-12-10       Impact factor: 2.316

3.  Specificity of antisense oligonucleotides in vivo.

Authors:  T M Woolf; D A Melton; C G Jennings
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-15       Impact factor: 11.205

Review 4.  Heterologous expression of calcium channels.

Authors:  J Nargeot; N Dascal; H A Lester
Journal:  J Membr Biol       Date:  1992-03       Impact factor: 1.843

Review 5.  Gene modulation for treating liver fibrosis.

Authors:  Kun Cheng; Ram I Mahato
Journal:  Crit Rev Ther Drug Carrier Syst       Date:  2007       Impact factor: 4.889

6.  The role of stress proteins in prostate cancer.

Authors:  Alan So; Boris Hadaschik; Richard Sowery; Martin Gleave
Journal:  Curr Genomics       Date:  2007-06       Impact factor: 2.236

7.  Inhibition of translation initiation by antisense oligonucleotides via an RNase-H independent mechanism.

Authors:  C Boiziau; R Kurfurst; C Cazenave; V Roig; N T Thuong; J J Toulmé
Journal:  Nucleic Acids Res       Date:  1991-03-11       Impact factor: 16.971

8.  A lineage-specific protein kinase crucial for myeloid maturation.

Authors:  D Semizarov; D Glesne; A Laouar; K Schiebel; E Huberman
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-22       Impact factor: 11.205

9.  Inhibition of NF-kappa B-Rel A expression by antisense oligodeoxynucleotides suppresses synthesis of urokinase-type plasminogen activator (uPA) but not its inhibitor PAI-1.

Authors:  U Reuning; O Wilhelm; T Nishiguchi; L Guerrini; F Blasi; H Graeff; M Schmitt
Journal:  Nucleic Acids Res       Date:  1995-10-11       Impact factor: 16.971

10.  Iron-dependent protection of the Synechococcus ferredoxin I transcript against nucleolytic degradation requires cis-regulatory sequences in the 5' part of the messenger RNA.

Authors:  A Bovy; J de Kruif; G de Vrieze; M Borrias; P Weisbeek
Journal:  Plant Mol Biol       Date:  1993-09       Impact factor: 4.076
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