Preparation of polysulfone materials on nickel foam for solid-phase microextraction of floxacin in water and biological samples.

Solid-phase microextraction with polysulfone and molecularly imprinted polymers as coating on nickel foam were used to adsorb and enrich floxacin drugs. The preparation method is simple and reproducible to obtain the materials with controlled thickness. After evaluation by scanning electron microscope and various adsorption experiments, the materials were used to adsorb analytes in water samples and biological samples. Coupling with chromatographic analysis, the method recoveries are satisfactory with 90.0-104.8% and 79.31-107.1% for water and biological samples. The method repeatability by intra- and interday experiments shows that the RSD values for water and biological samples were 1.0-9.9% and 1.7-10.3%, with the quantitative limits of three floxacin drugs as 3.0-6.2 μg L-1. Graphical Abstract Preparation diagram of polysulfone material.