Effect of scaling and root planing with and without adjunct use of an essential-oil-based mouthwash on whole salivary interleukin-1β levels in patients with periodontal disease: A short-term follow-up study.

OBJECTIVE: The aim of the present short-term follow-up study was to assess the effect of scaling and root planing (SRP) with and without adjunct use of an essential-oil-based mouthwash (EOBM) on whole salivary interleukin (IL)-1beta (β) levels in patients with periodontal disease.
METHODS: Ninety individuals with periodontal disease were divided into two groups. Patients in group 1 underwent SRP and were instructed to rinse with 10 mL of an EOBM twice daily for 30 days. Patients in group 2 underwent SRP and were instructed to rinse with 10 mL of water twice daily for 30 days. Whole saliva samples were collected, and IL-1β levels were measured at baseline and after 60 days of treatment. P-values < 0.05 were considered statistically significant.
RESULTS: At baseline, whole salivary IL-1β levels were comparable among patients in groups 1 (135.6 ± 13.5 μg/mL) and 2 (141.2 ± 5.4 μg/mL). After 60 days of follow-up, there is a significant decrease in whole salivary IL-1β levels among patients in group 1 (10.2 ± 6.4 μg/mL) as compared to those in group 2 (56.6 ± 10.2 μg/mL) (P < 0.01).
CONCLUSION: SRP, when performed with adjunct use of an EOBM, is more effective in reducing whole salivary IL-1β levels as compared to when SRP is performed without the use of an EOBM.

RCT Entities:   Population Interventions Outcomes