Literature DB >> 28246626

Myocutaneous Mucormycosis in a Diabetic Burnt Patient Led to Upper Extremity Amputation; A Case Report.

Mehdi Ayaz1, Reza Moein2.   

Abstract

Mucormycosis is a rare opportunistic fungal infection that can implicate cranial sinuses, brain, lungs, gastrointestinal tract and skin. Although it can occur in patients with competent and incompetent immunity such as patients with diabetes mellitus, lymphoma, leukemia and burns, but it has an aggressive, malignant and lethal course in patients with incompetent immunity. To enforce the importance of burn in patients with underlaying diseases such as diabetes, we are going to report a rare case of diabetic burnt patient complicated by right upper extremity myocutaneous mucormycosis. We selected this case to emphasis the importance of underlying disease (diabetes mellitus) with cutaneous burn, aggressive treatment of fungal infection in these patients and referring such case to burn center to prevent catastrophic results. A 50-year-old woman was introduced to us after several days of medical and surgical care of right upper extremity and trunk split-thickness burn. Due to gross muscle necrosis of right upper extremity and poor general condition of the patient, she was taken to the operating room that led to right upper extremity amputation and several times of aggressive debridement to save her life. Pathologic report was indicative of mucormycosis. We can conclude from this case that: 1) Burn, even partially thickness and with little body surface area, should be referred to burn center for better care 2) No response to usual medical treatment should make us more sensitive to consider the unusual causes of infection such as fungi 3) Suspected dead tissues should be excised aggressively especially if suspiciousness to wound sepsis and fungal infection is present especially in an immunocompromised patient.

Entities:  

Keywords:  American Burn Association (ABA); Diabetes; Extremity amputation; Mucormycosis; Partial thickness burn

Year:  2017        PMID: 28246626      PMCID: PMC5316139     

Source DB:  PubMed          Journal:  Bull Emerg Trauma        ISSN: 2322-2522


  7 in total

1.  Predisposing Factors for Mucormycosis in Patients with Diabetes Mellitus; An Experience of 21 Years in Southern Iran.

Authors:  Amene S Sarvestani; Gholamreza Pishdad; Shahram Bolandparvaz
Journal:  Bull Emerg Trauma       Date:  2013-10

2.  Opportunistic filamentous mycoses: aspergillosis, mucormycosis, phaeohyphomycosis and hyalohyphomycosis.

Authors:  Ana María Perusquía-Ortiz; Denisse Vázquez-González; Alexandro Bonifaz
Journal:  J Dtsch Dermatol Ges       Date:  2012-09       Impact factor: 5.584

3.  [Primary cutaneous mucormycosis: two case reports and review of the literature].

Authors:  Oscar Tapia E; Carolina Chahín A; Carla Concha F
Journal:  Rev Chilena Infectol       Date:  2011-07-14       Impact factor: 0.520

Review 4.  Pathogenesis of mucormycosis.

Authors:  Ashraf S Ibrahim; Brad Spellberg; Thomas J Walsh; Dimitrios P Kontoyiannis
Journal:  Clin Infect Dis       Date:  2012-02       Impact factor: 9.079

Review 5.  Epidemiology and clinical manifestations of mucormycosis.

Authors:  George Petrikkos; Anna Skiada; Olivier Lortholary; Emmanuel Roilides; Thomas J Walsh; Dimitrios P Kontoyiannis
Journal:  Clin Infect Dis       Date:  2012-02       Impact factor: 9.079

Review 6.  Gangrenous cutaneous mucormycosis caused by Rhizopus oryzae: a case report and review of primary cutaneous mucormycosis in China over Past 20 years.

Authors:  HouMin Li; Sonia Kay Hwang; Cheng Zhou; Juan Du; JianZhong Zhang
Journal:  Mycopathologia       Date:  2013-04-25       Impact factor: 2.574

7.  Rare case of primary cutaneous mucormycosis of the hand caused by Rhizopus microsporus in an immunocompetent patient.

Authors:  Rajesh Verma; Velu Nair; Biju Vasudevan; Pragasam Vijendran; Vineet Behera; Shekhar Neema
Journal:  Int J Dermatol       Date:  2013-10-29       Impact factor: 2.736

  7 in total

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