Therese Haugdahl Nøst1, Torkjel Manning Sandanger2, Evert Nieboer3, Jon Øyvind Odland4, Knut Breivik5. 1. NILU - Norwegian Institute for Air Research, The FRAM Centre, P.O. Box 6606 Langnes, NO-9296 Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, UiT - The Arctic University of Norway, P.O. Box 6050 Langnes, NO-9037 Tromsø, Norway. Electronic address: therese.h.nost@uit.no. 2. NILU - Norwegian Institute for Air Research, The FRAM Centre, P.O. Box 6606 Langnes, NO-9296 Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, UiT - The Arctic University of Norway, P.O. Box 6050 Langnes, NO-9037 Tromsø, Norway. 3. Department of Biochemistry and Biomedical Sciences, McMaster University,1280 Main Street West, Hamilton, Ontario, Canada. 4. Department of Community Medicine, Faculty of Health Sciences, UiT - The Arctic University of Norway, P.O. Box 6050 Langnes, NO-9037 Tromsø, Norway. 5. NILU - Norwegian Institute for Air Research, P.O. Box 100, NO-2027 Kjeller, Norway; Department of Chemistry, University of Oslo, P.O. Box 1033, NO-0315 Oslo, Norway.
Abstract
BACKGROUND: In this short communication, our focus is on the relationship between human concentrations of select persistent organic pollutants (POPs) and environmental emissions. It is based on a longitudinal study (1979-2007) conducted in Norway. OBJECTIVES: Our aim was to extract general insights from observed and predicted temporal trends in human concentrations of 49 POPs to assist in the design and interpretation of future monitoring studies. DISCUSSION: Despite considerable decline for polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) since 1986, the sum of the targeted POPs increased from 1979 until 2001, with per- and polyfluorinated alkyl substances (PFASs) dominating recent blood burden measurements. Specifically, the time trends in serum concentrations of POPs, exemplified by PCB-153, 1,1'-(2,2,2-Trichloroethane-1,1-diyl)bis(4-chlorobenzene) (DDT) and perfluorooctane sulfonic acid (PFOS), resembled the trends in available data on their emissions, production or use. These observations suggest that interpretations of human biomonitoring data on persistent compounds must consider historic emissions, which likely vary spatially across the globe. Based on the different temporal trends observed across POP groups, it is evident that generalizations regarding temporal aspects have limitations. CONCLUSION: The discussion herein underscores the importance of understanding temporal variations in environmental emissions when designing and interpreting human biomonitoring studies.
BACKGROUND: In this short communication, our focus is on the relationship between human concentrations of select persistent organic pollutants (POPs) and environmental emissions. It is based on a longitudinal study (1979-2007) conducted in Norway. OBJECTIVES: Our aim was to extract general insights from observed and predicted temporal trends in human concentrations of 49 POPs to assist in the design and interpretation of future monitoring studies. DISCUSSION: Despite considerable decline for polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) since 1986, the sum of the targeted POPs increased from 1979 until 2001, with per- and polyfluorinated alkyl substances (PFASs) dominating recent blood burden measurements. Specifically, the time trends in serum concentrations of POPs, exemplified by PCB-153, 1,1'-(2,2,2-Trichloroethane-1,1-diyl)bis(4-chlorobenzene) (DDT) and perfluorooctane sulfonic acid (PFOS), resembled the trends in available data on their emissions, production or use. These observations suggest that interpretations of human biomonitoring data on persistent compounds must consider historic emissions, which likely vary spatially across the globe. Based on the different temporal trends observed across POP groups, it is evident that generalizations regarding temporal aspects have limitations. CONCLUSION: The discussion herein underscores the importance of understanding temporal variations in environmental emissions when designing and interpreting human biomonitoring studies.
Authors: Pernilla Carlsson; Knut Breivik; Eva Brorström-Lundén; Ian Cousins; Jesper Christensen; Joan O Grimalt; Crispin Halsall; Roland Kallenborn; Khaled Abass; Gerhard Lammel; John Munthe; Matthew MacLeod; Jon Øyvind Odland; Janet Pawlak; Arja Rautio; Lars-Otto Reiersen; Martin Schlabach; Irene Stemmler; Simon Wilson; Henry Wöhrnschimmel Journal: Environ Sci Pollut Res Int Date: 2018-06-28 Impact factor: 4.223
Authors: Miquel Porta; José Pumarega; André F S Amaral; Jeanine M Genkinger; Judit Camargo; Lorelei Mucci; Juan Alguacil; Magda Gasull; Xuehong Zhang; Eva Morales; Mar Iglesias; Shuji Ogino; Lawrence S Engel Journal: Environ Res Date: 2020-06-11 Impact factor: 6.498