Literature DB >> 2824530

Fibroblast growth factor: structural and biological properties.

D Gospodarowicz1, G Neufeld, L Schweigerer.   

Abstract

Basic fibroblast growth factor (FGF) and acidic FGF are two closely related peptides that are multifunctional. They control proliferation, differentiation, and various other cellular functions in cells derived from the mesoderm and the neuroectoderm. The structural properties, genomic organization, and biological functions of both peptides in vitro or in vivo are reviewed. Their marked ability to enhance formation of connective tissue and vascular capillaries, as well as their involvement in limb regeneration, suggest several possible therapeutic applications.

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Year:  1987        PMID: 2824530     DOI: 10.1002/jcp.1041330405

Source DB:  PubMed          Journal:  J Cell Physiol Suppl        ISSN: 0737-1462


  64 in total

Review 1.  Role of cytokines in the pathogenesis of posterior capsule opacification.

Authors:  W R Meacock; D J Spalton; M R Stanford
Journal:  Br J Ophthalmol       Date:  2000-03       Impact factor: 4.638

2.  Characterization of PC12 cell proliferation and differentiation-stimulated by ECM adhesion proteins and neurotrophic factors.

Authors:  Darlene G Attiah; Ross A Kopher; Tejal A Desai
Journal:  J Mater Sci Mater Med       Date:  2003-11       Impact factor: 3.896

3.  Heparin-binding growth factors and their receptors.

Authors:  B B Olwin
Journal:  Cytotechnology       Date:  1989-12       Impact factor: 2.058

4.  Epigenetic Interactions and Gene Expression in Peri-Implantation Mouse Embryo Development.

Authors:  Jean J Latimer; Roger A Pedersen
Journal:  Mod Cell Biol       Date:  1993

Review 5.  Fetal growth signals.

Authors:  R D Milner; D J Hill
Journal:  Arch Dis Child       Date:  1989-01       Impact factor: 3.791

6.  Expression of acidic and basic fibroblast growth factors in the substantia nigra of rat, monkey, and human.

Authors:  A J Bean; R Elde; Y H Cao; C Oellig; C Tamminga; M Goldstein; R F Pettersson; T Hökfelt
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-15       Impact factor: 11.205

7.  Induction of vascular endothelial tubular morphogenesis by human glioma cells. A model system for tumor angiogenesis.

Authors:  T Abe; K Okamura; M Ono; K Kohno; T Mori; S Hori; M Kuwano
Journal:  J Clin Invest       Date:  1993-07       Impact factor: 14.808

8.  Species-specific differences in the mitogenic activity of heparin-binding growth factors in the sera of various mammals.

Authors:  Y Yonezawa; H Kondo; R Hirai; K Kaji; K Nishikawa
Journal:  Experientia       Date:  1992-03-15

9.  Differential purification of autocrine motility factor derived from a murine protein-free fibrosarcoma.

Authors:  H Watanabe; K Kanbe; M Chigira
Journal:  Clin Exp Metastasis       Date:  1994-03       Impact factor: 5.150

10.  Scintigraphic detection of xenografted tumors producing human basic fibroblast growth factor.

Authors:  H Kobayashi; H Sakahara; M Hosono; M Shirato; J Konishi; J A Takahashi; Y Oda; H Kikuchi; K Endo; Y Kozai
Journal:  Cancer Immunol Immunother       Date:  1993-10       Impact factor: 6.968

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