Literature DB >> 28245021

A mitochondria-targeting supramolecular photosensitizer based on pillar[5]arene for photodynamic therapy.

Leilei Rui1, Yudong Xue1, Yong Wang2, Yun Gao1, Weian Zhang1.   

Abstract

A mitochondria-targeting supramolecular photosensitizer system TPP-QAS/WP5/DTAB was constructed based on a host-guest inclusion complex. The supramolecular system could efficiently release and activate TPP-QASs in an acidic environment, which have been demonstrated to preferentially accumulate in mitochondria. Singlet oxygen (1O2) could be in situ generated in mitochondria under light irradiation, further enhancing the PDT efficacy.

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Year:  2017        PMID： 28245021     DOI： 10.1039/c7cc00950j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433.

Authors:  Susan Monro; Katsuya L Colón; Huimin Yin; John Roque; Prathyusha Konda; Shashi Gujar; Randolph P Thummel; Lothar Lilge; Colin G Cameron; Sherri A McFarland
Journal:  Chem Rev       Date:  2018-10-08       Impact factor: 60.622

2.  Supramolecular peptide constructed by molecular Lego allowing programmable self-assembly for photodynamic therapy.

Authors:  Huangtianzhi Zhu; Huanhuan Wang; Bingbing Shi; Liqing Shangguan; Weijun Tong; Guocan Yu; Zhengwei Mao; Feihe Huang
Journal:  Nat Commun       Date:  2019-06-03       Impact factor: 14.919

Review 3.  Supramolecular nanotheranostics based on pillarenes.

Authors:  Nan Song; Xin-Yue Lou; Lianjun Ma; Hui Gao; Ying-Wei Yang
Journal:  Theranostics       Date:  2019-05-18       Impact factor: 11.556

4.  A supramolecular hydrophobic guest transport system based on a biological macrocycle.

Authors:  Yan Ge; Xin Shen; Hongqian Cao; Yuchong Hao; Lin Jin; Jie Shang; Yangxin Wang; Tiezheng Pan; Zhenhui Qi
Journal:  RSC Adv       Date:  2019-11-22       Impact factor: 4.036

5.  Cancer-mitochondria-targeted photodynamic therapy with supramolecular assembly of HA and a water soluble NIR cyanine dye.

Authors:  Ajesh P Thomas; L Palanikumar; M T Jeena; Kibeom Kim; Ja-Hyoung Ryu
Journal:  Chem Sci       Date:  2017-10-13       Impact factor: 9.825
  5 in total

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