Literature DB >> 2824415

Transforming genes in human hepatomas detected by a tumorigenicity assay.

Y Yuasa1, K Sudo.   

Abstract

Two transforming sequences in human hepatomas were detected by means of a tumorigenicity assay in nude mice using transfected NIH3T3 cells. Through hybridization with known oncogene probes, the transforming gene in one hepatoma was found to be the human hst gene. The transforming sequence in the other hepatoma showed no sequence homology with any of the oncogenes examined.

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Year:  1987        PMID： 2824415

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN： 0910-5050


  5 in total

1.  Human HST1 (HSTF1) gene maps to chromosome band 11q13 and coamplifies with the INT2 gene in human cancer.

Authors:  M C Yoshida; M Wada; H Satoh; T Yoshida; H Sakamoto; K Miyagawa; J Yokota; T Koda; M Kakinuma; T Sugimura
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205

2.  The mouse homologue of hst/k-FGF: sequence, genome organization and location relative to int-2.

Authors:  S Brookes; R Smith; J Thurlow; C Dickson; G Peters
Journal:  Nucleic Acids Res       Date:  1989-06-12       Impact factor: 16.971

3.  Possible dissociation of the heparin-binding and mitogenic activities of heparin-binding (acidic fibroblast) growth factor-1 from its receptor-binding activities by site-directed mutagenesis of a single lysine residue.

Authors:  W H Burgess; A M Shaheen; M Ravera; M Jaye; P J Donohue; J A Winkles
Journal:  J Cell Biol       Date:  1990-11       Impact factor: 10.539

4.  Alterations of mouse proto-oncogenes in sarcomas induced after transplantation of human tumors in athymic nude mice.

Authors:  Y Yuasa; H Yamazaki; K Maruo; Y Ueyama; M Shibuya; N Tamaoki
Journal:  Jpn J Cancer Res       Date:  1990-04

5.  Amplification of the hst-1 gene in human esophageal carcinomas.

Authors:  T Tsuda; H Nakatani; T Matsumura; K Yoshida; E Tahara; T Nishihira; H Sakamoto; T Yoshida; M Terada; T Sugimura
Journal:  Jpn J Cancer Res       Date:  1988-05
  5 in total

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