Literature DB >> 28244018

Intra-articular benign bone lesions treated with Magnetic Resonance-guided Focused Ultrasound (MRgFUS): imaging follow-up and clinical results.

Francesco Arrigoni1, Antonio Barile2, Luigi Zugaro2, Alessandra Splendiani2, Ernesto Di Cesare2, Ferdinando Caranci3, Anna Maria Ierardi4, Chiara Floridi4, Alessio Salvatore Angileri5, Alfonso Reginelli6, Luca Brunese3, Carlo Masciocchi2.   

Abstract

Purpose of this study was to evaluate the employment of MRI-guided Focused Ultrasound (MRgFUS) for treatment of intra-articular benign bone lesions as alternative to surgery, and to monitor the success of the treatment on CT and MRI images. From March 2011 to August 2013, 14 intra-articular benign bone lesions were treated with MRgFUS. All patients were studied by CT and MR imaging. Pain was measured using the visual analogue scale (VAS) before and after treatment (6 and 12 months). All patients in our series demonstrated regression in painful symptomatology during screening. A significant drop in the mean VAS pain score (from 7.8 to 0.6) was observed at 12-month follow-up, and pain medication was no longer needed after treatment. No complications were observed. Three diagnostic imaging signs were found suggesting absence of biological activity and confirming the clinical findings: calcification of the treated lesion, lack of contrast enhancement and disappearance of bone oedema around the lesions.
CONCLUSION: the employment of MRgFUS is safe and effective in the treatment of intra-articular benign bone lesions. The clinical outcome is satisfactory, and the success of the treatment is confirmed by diagnostic imaging.

Entities:  

Keywords:  Benign bone lesions; Interventional radiology; Intrarticular bone lesions; MRgFUS; Osteoid Osteoma; Thermoablation

Mesh:

Year:  2017        PMID: 28244018     DOI: 10.1007/s12032-017-0904-7

Source DB:  PubMed          Journal:  Med Oncol        ISSN: 1357-0560            Impact factor:   3.064


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