Literature DB >> 28240181

Recent Advances in Synthesis and Identification of Cyclic Peptides for Bioapplications.

Yong Siang Ong1, Liqian Gao1, Karunakaran A Kalesh2, Zhiqiang Yu3, Jigang Wang4, Chengcheng Liu5, Yiwen Li6, Hongyan Sun7, Su Seong Lee1.   

Abstract

Cyclic peptides, owing to their good stability, high resistance to exo- and to some extent endo-peptidases, enhanced binding affinity and selectivity towards target biomolecules, are actively investigated as biochemical tools and therapeutic agents. In this review, we discuss various commonly utilized synthetic strategies for cyclic peptides and peptoids (peptidomimetics), their important screening methods to identify the bioactive cyclic peptides and peptoids such as combinatorial beadbased peptide library, phage display, mRNA display etc. and recent advances in their applications as bioactive compounds. Lastly, we also make a summary and provide an outlook of the research area. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Bead-based library; Computational; Cyclic peptide; Cyclization; Phage display; mRNA display

Mesh：

Substances：

Year:  2017        PMID： 28240181     DOI： 10.2174/1568026617666170224121658

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN： 1568-0266            Impact factor:   3.295


  8 in total

Review 1.  Development of Duramycin-Based Molecular Probes for Cell Death Imaging.

Authors:  Dongjian Zhang; Meng Gao; Qiaomei Jin; Yicheng Ni; Huailiang Li; Cuihua Jiang; Jian Zhang
Journal:  Mol Imaging Biol       Date:  2022-02-10       Impact factor: 3.484

2.  Organometallic AlaM Reagents for Umpolung Peptide Diversification.

Authors:  Feng Zhu; Wyatt C Powell; Ruiheng Jing; Maciej A Walczak
Journal:  Chem Catal       Date:  2021-06-28

3.  Cyclic RGD Pentapeptide Cilengitide Enhances Efficacy of Gefitinib on TGF-β1-Induced Epithelial-to-Mesenchymal Transition and Invasion in Human Non-Small Cell Lung Cancer Cells.

Authors:  Jisu Jeong; Jiyeon Kim
Journal:  Front Pharmacol       Date:  2021-03-24       Impact factor: 5.810

4.  Simplified Head-to-Tail Cyclic Polypeptides as Biomaterial-Associated Antimicrobials with Endotoxin Neutralizing and Anti-Inflammatory Capabilities.

Authors:  Na Dong; Chensi Wang; Xinran Li; Yuming Guo; Xiaoli Li
Journal:  Int J Mol Sci       Date:  2019-11-25       Impact factor: 5.923

Review 5.  Secondary Metabolites of the Genus Amycolatopsis: Structures, Bioactivities and Biosynthesis.

Authors:  Zhiqiang Song; Tangchang Xu; Junfei Wang; Yage Hou; Chuansheng Liu; Sisi Liu; Shaohua Wu
Journal:  Molecules       Date:  2021-03-26       Impact factor: 4.411

6.  Combination Effect of Cilengitide with Erlotinib on TGF-β1-Induced Epithelial-to-Mesenchymal Transition in Human Non-Small Cell Lung Cancer Cells.

Authors:  Jisu Jeong; Jiyeon Kim
Journal:  Int J Mol Sci       Date:  2022-03-22       Impact factor: 5.923

7.  Physiological effects of a novel artificially synthesized antimalarial cyclic peptide: Mahafacyclin B.

Authors:  Yuko Fujita; Panpaki Seekaki; Norichika Ogata; Kazuhiro Chiba
Journal:  PLoS One       Date:  2017-11-30       Impact factor: 3.240

Review 8.  A Review of Resveratrol as a Potent Chemoprotective and Synergistic Agent in Cancer Chemotherapy.

Authors:  Qicai Xiao; Wangshu Zhu; Wei Feng; Su Seong Lee; Albert Wingnang Leung; Jun Shen; Liqian Gao; Chuanshan Xu
Journal:  Front Pharmacol       Date:  2019-01-09       Impact factor: 5.810
  8 in total

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