Literature DB >> 28240172

Clinical Applications of Personalized Medicine: A New Paradigm and Challenge.

Mariantonia Di Sanzo1, Luigi Cipolloni2, Marina Borro3, Raffaele La Russa1, Alessandro Santurro1, Matteo Scopetti1, Maurizio Simmaco3, Paola Frati4.   

Abstract

The personalized medicine is an emergent and rapidly developing method of clinical practice that uses new technologies to provide decisions in regard to the prediction, prevention, diagnosis and treatment of disease. A continuous evolution of technology and the developments in molecular diagnostics and genomic analysis increased the possibility of an even more understanding and interpretation of the human genome and exome, allowing a "personalized" approach to clinical care, so that the concepts of "Systems Medicine" and "System Biology" are actually increasing. The purpose of this study is to evaluate the personalized medicine about its indications and benefits, actual clinical applications and future perspectives as well as its issues and health care implications. A careful review of the scientific literature on this field that highlighted the applicability and usefulness of this new medical approach as well as the fact that personalized medicine strategy is even more increasing in numerous fields of applications. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Personalized medicine; genetic tests; genomic medicine; healthcare; medicine system; molecular diagnostic; pharmacogenomics; precision medicine

Mesh:

Year:  2017        PMID: 28240172     DOI: 10.2174/1389201018666170224105600

Source DB:  PubMed          Journal:  Curr Pharm Biotechnol        ISSN: 1389-2010            Impact factor:   2.837


  20 in total

Review 1.  Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair.

Authors:  Wei Cai; Tuo Yang; Huan Liu; Lijuan Han; Kai Zhang; Xiaoming Hu; Xuejing Zhang; Ke-Jie Yin; Yanqin Gao; Michael V L Bennett; Rehana K Leak; Jun Chen
Journal:  Prog Neurobiol       Date:  2017-10-12       Impact factor: 11.685

Review 2.  Mesenchymal stem cells in neurodegenerative diseases: Opinion review on ethical dilemmas.

Authors:  Matteo Scopetti; Alessandro Santurro; Vittorio Gatto; Raffaele La Russa; Federico Manetti; Stefano D'Errico; Paola Frati; Vittorio Fineschi
Journal:  World J Stem Cells       Date:  2020-03-26       Impact factor: 5.326

Review 3.  When Tissue is an Issue the Liquid Biopsy is Nonissue: A Review.

Authors:  July Rodríguez; Jenny Avila; Christian Rolfo; Alejandro Ruíz-Patiño; Alessandro Russo; Luisa Ricaurte; Camila Ordóñez-Reyes; Oscar Arrieta; Zyanya Lucia Zatarain-Barrón; Gonzalo Recondo; Andrés F Cardona
Journal:  Oncol Ther       Date:  2021-03-10

Review 4.  Society and personal genome data.

Authors:  Anna Middleton
Journal:  Hum Mol Genet       Date:  2018-05-01       Impact factor: 6.150

Review 5.  Stem Cell Research and Clinical Translation: A Roadmap about Good Clinical Practice and Patient Care.

Authors:  Paola Frati; Matteo Scopetti; Alessandro Santurro; Vittorio Gatto; Vittorio Fineschi
Journal:  Stem Cells Int       Date:  2017-09-27       Impact factor: 5.443

Review 6.  Precision and Personalized Medicine: How Genomic Approach Improves the Management of Cardiovascular and Neurodegenerative Disease.

Authors:  Oriana Strianese; Francesca Rizzo; Michele Ciccarelli; Gennaro Galasso; Ylenia D'Agostino; Annamaria Salvati; Carmine Del Giudice; Paola Tesorio; Maria Rosaria Rusciano
Journal:  Genes (Basel)       Date:  2020-07-06       Impact factor: 4.096

Review 7.  Human Organ-Specific 3D Cancer Models Produced by the Stromal Self-Assembly Method of Tissue Engineering for the Study of Solid Tumors.

Authors:  Vincent Roy; Brice Magne; Maude Vaillancourt-Audet; Mathieu Blais; Stéphane Chabaud; Emil Grammond; Léo Piquet; Julie Fradette; Isabelle Laverdière; Véronique J Moulin; Solange Landreville; Lucie Germain; François A Auger; François Gros-Louis; Stéphane Bolduc
Journal:  Biomed Res Int       Date:  2020-04-13       Impact factor: 3.411

8.  Cephalosporins' Cross-Reactivity and the High Degree of Required Knowledge. Case Report and Review of the Literature.

Authors:  Stefano D'Errico; Paola Frati; Martina Zanon; Eleonora Valentinuz; Federico Manetti; Matteo Scopetti; Alessandro Santurro; Vittorio Fineschi
Journal:  Antibiotics (Basel)       Date:  2020-04-25

9.  Assessing and measuring financial sustainability model of the Spanish HIV HGM BioBank.

Authors:  Irene Consuegra Fernández; Isabel García Merino; María Ángeles Muñoz-Fernández
Journal:  J Transl Med       Date:  2020-01-06       Impact factor: 5.531

Review 10.  hiPSCs Derived Cardiac Cells for Drug and Toxicity Screening and Disease Modeling: What Micro- Electrode-Array Analyses Can Tell Us.

Authors:  Sophie Kussauer; Robert David; Heiko Lemcke
Journal:  Cells       Date:  2019-10-28       Impact factor: 6.600

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