Fernando Poblete1, Nicolas A Barticevic2, Maria Soledad Zuzulich3, Rodrigo Portilla4, Alvaro Castillo-Carniglia5, Jaime C Sapag2, Luis Villarroel1, Brena F Sena6, Magdalena Galarce7. 1. School of Medicine, Department of Public Health, Pontificia Universidad Católica de Chile, Santiago, Chile. 2. School of Medicine, Department of Family Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile. 3. School of Medicine, Nursing School, Pontificia Universidad Católica de Chile, Santiago, Chile. 4. Research Department, National Service for Prevention and Rehabilitation of Drug and Alcohol Consumption, Santiago, Chile. 5. Department of Emergency Medicine, UC Davis School of Medicine, Violence Prevention Research Program, Sacramento, CA, USA. 6. Columbia University School of Public Health, New York, NY, USA. 7. School of Medicine, Center for Study of Addiction, Pontificia Universidad Catolica de Chile, Santiago, Chile.
Abstract
AIM: To study the effectiveness of a brief intervention (BI) associated with the ASSIST (Alcohol Smoking and Substance Involvement Screening Test) for alcohol and illicit drug use as part of a systematic screening program implemented in primary care. DESIGN: A multi-center randomized open-label trial stratified using the ASSIST-specific substance involvement score (for alcohol, scores ranged from 11 to 15 and 16 to 20; and for the other substances from 4 to 12 and 13 to 20). SETTING: A total of 19 primary care centers (n = 520), eight emergency rooms (n = 195) and five police stations (n = 91) were evaluated. PARTICIPANTS: A total of 12 217 people aged between 19 and 55 years were screened for moderate alcohol and drug use risk as defined by the ASSIST Chilean version. A total of 806 non-treatment-seekers were randomized. INTERVENTION AND COMPARISON: ASSIST-linked BI (n = 400) compared with an informational pamphlet on risk associated with substance use (n = 406). MEASUREMENTS: Total ASSIST alcohol and illicit involvement score (ASSIST-AI), and ASSIST-specific score for alcohol, cannabis and cocaine at baseline and at 3-month follow-up. FINDINGS: Sixty-two per cent of participants completed follow-up. An intention-to-treat analysis showed no difference between the two groups for the ASSIST-AI score [mean difference (MD) = - 0.17, confidence interval (CI) = -1.87, 2.20], either for specific scores alcohol (MD = 0.18, CI = -1.45, 1.10), cannabis (MD = -0.62, CI = -0.89, 2.14) or cocaine (MD = -0.79, CI = -2.89, 4.47). CONCLUSION: It is not clear whether a brief intervention associated with the Alcohol Smoking and Substance Involvement Screening Test is more effective than an informational pamphlet in reducing alcohol and illicit substance consumption in non-treatment-seeking, primary care users with moderate risk.
RCT Entities:
AIM: To study the effectiveness of a brief intervention (BI) associated with the ASSIST (Alcohol Smoking and Substance Involvement Screening Test) for alcohol and illicit drug use as part of a systematic screening program implemented in primary care. DESIGN: A multi-center randomized open-label trial stratified using the ASSIST-specific substance involvement score (for alcohol, scores ranged from 11 to 15 and 16 to 20; and for the other substances from 4 to 12 and 13 to 20). SETTING: A total of 19 primary care centers (n = 520), eight emergency rooms (n = 195) and five police stations (n = 91) were evaluated. PARTICIPANTS: A total of 12 217 people aged between 19 and 55 years were screened for moderate alcohol and drug use risk as defined by the ASSIST Chilean version. A total of 806 non-treatment-seekers were randomized. INTERVENTION AND COMPARISON: ASSIST-linked BI (n = 400) compared with an informational pamphlet on risk associated with substance use (n = 406). MEASUREMENTS: Total ASSIST alcohol and illicit involvement score (ASSIST-AI), and ASSIST-specific score for alcohol, cannabis and cocaine at baseline and at 3-month follow-up. FINDINGS: Sixty-two per cent of participants completed follow-up. An intention-to-treat analysis showed no difference between the two groups for the ASSIST-AI score [mean difference (MD) = - 0.17, confidence interval (CI) = -1.87, 2.20], either for specific scores alcohol (MD = 0.18, CI = -1.45, 1.10), cannabis (MD = -0.62, CI = -0.89, 2.14) or cocaine (MD = -0.79, CI = -2.89, 4.47). CONCLUSION: It is not clear whether a brief intervention associated with the Alcohol Smoking and Substance Involvement Screening Test is more effective than an informational pamphlet in reducing alcohol and illicit substance consumption in non-treatment-seeking, primary care users with moderate risk.
Authors: Dominic Hodgkin; Wenwu Gao; Mary Jo Larson; Charles E Drebing; Elizabeth L Merrick; Marianne Pugatch; Constance M Horgan; Galina Zolotusky; Nancy M Petry; Richard Saitz Journal: J Addict Med Date: 2020 May/Jun Impact factor: 4.647
Authors: Jan Klimas; Christopher Fairgrieve; Helen Tobin; Catherine-Anne Field; Clodagh Sm O'Gorman; Liam G Glynn; Eamon Keenan; Jean Saunders; Gerard Bury; Colum Dunne; Walter Cullen Journal: Cochrane Database Syst Rev Date: 2018-12-05
Authors: Abhijit Nadkarni; Urvita Bhatia; Andre Bedendo; Tassiane Cristine Santos de Paula; Joanna Gonçalves de Andrade Tostes; Lidia Segura-Garcia; Marcela Tiburcio; Sven Andréasson Journal: Int J Ment Health Syst Date: 2022-08-08
Authors: Nicolas A Barticevic; Fernando Poblete; Soledad M Zuzulich; Victoria Rodriguez; Laura Bradshaw Journal: Trials Date: 2020-07-31 Impact factor: 2.279