Literature DB >> 28239790

Antibodies to Glutamate Reversed the Amnesic Effects of Proinflammatory S100A9 Protein Fibrils in Aged C57Bl/6 Mice.

M A Gruden1, T V Davydova2, V G Fomina2, L A Vetrile2, L A Morozova-Roche3, R D E Sewell4.   

Abstract

Chronic intranasal administration of fibrillar structures of proinflammatory S100A9 protein impaired passive avoidance learning in old C57Bl/6 mice. Combined treatment with S100A9 fibrils and antibodies to glutamate was followed by an increase in horizontal locomotor activity of animals in the open-field test and did not disturb spatial memory.

Entities:  

Keywords:  S100A9 fibrils; amnesia; antibodies to glutamate; locomotor activity; spatial memory

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Year:  2017        PMID： 28239790     DOI： 10.1007/s10517-017-3632-2

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  3 in total

1.  Effects of Antibodies to Glutamate on Cerebral Expression of the Tnfrsf1A Gene under Conditions of Spatial Amnesia Induced by Proinflammatory Protein S100A9 Fibrils in Aging Mice.

Authors:  M A Gruden; T V Davydova; A M Ratmirov; R D E Sewell
Journal:  Bull Exp Biol Med       Date:  2021-11-19       Impact factor: 0.804

Review 2.  S100A8/A9 in Inflammation.

Authors:  Siwen Wang; Rui Song; Ziyi Wang; Zhaocheng Jing; Shaoxiong Wang; Jian Ma
Journal:  Front Immunol       Date:  2018-06-11       Impact factor: 7.561

3.  Delayed Behavioral and Neurochemical Effects of Anti-Glutamate Antibodies in Aging C57BL/6 Mice.

Authors:  T V Davydova; M A Gruden; V S Kudrin; V B Narkevich; L A Vetrile; I A Zakharova; R D E Sewell
Journal:  Bull Exp Biol Med       Date:  2021-05-28       Impact factor: 0.804
  3 in total

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