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Literature DB >> 28239240

Synthesis and screening of peptide libraries with free C-termini.

Abstract

Peptide libraries are useful tools to investigate the relationship between structure and function of proteins. The creation of peptide libraries with free C-termini presents unique synthetic challenges. In this review, methods for creating peptide libraries using either solid-phase peptide synthesis or phage display are described. Methods for screening such libraries and their application in studying several important biological problems are also reported.

Entities: CellLine Chemical Disease Gene Mutation Species

Keywords: C-terminal peptide libraries; combinatorial libraries; peptide libraries; phage display; protein libraries; screening; solid-phase peptide synthesis

Year: 2014 PMID： 28239240 PMCID： PMC5321655

Source DB: PubMed Journal: Curr Top Pept Protein Res ISSN： 0972-4524

59 in total

1. Combinatorial peptide on-resin analysis: optimization of static nanoelectrospray ionization technique for sequence determination.

Authors: K J Biederman; H Lee; C A Haney; M Kaczmarek; J A Buettner
Journal: J Pept Res Date: 1999-03

2. Analysis of PDZ domain-ligand interactions using carboxyl-terminal phage display.

Authors: G Fuh; M T Pisabarro; Y Li; C Quan; L A Lasky; S S Sidhu
Journal: J Biol Chem Date: 2000-07-14 Impact factor: 5.157

3. Distinct binding specificity of the multiple PDZ domains of INADL, a human protein with homology to INAD from Drosophila melanogaster.

Authors: P Vaccaro; B Brannetti; L Montecchi-Palazzi; S Philipp; M Helmer Citterich; G Cesareni; L Dente
Journal: J Biol Chem Date: 2001-08-16 Impact factor: 5.157

4. The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF.

Authors: Richard P Laura; Andrea S Witt; Heike A Held; Resi Gerstner; Kurt Deshayes; Michael F T Koehler; Kenneth S Kosik; Sachdev S Sidhu; Laurence A Lasky
Journal: J Biol Chem Date: 2002-01-30 Impact factor: 5.157

5. PDZ domains: troubles in classification.

Authors: Paola Vaccaro; Luciana Dente
Journal: FEBS Lett Date: 2002-02-13 Impact factor: 4.124

Review 6. Mechanisms underlying ubiquitination.

Authors: C M Pickart
Journal: Annu Rev Biochem Date: 2001 Impact factor: 23.643

7. A novel peptide-based encoding system for "one-bead one-compound" peptidomimetic and small molecule combinatorial libraries.

Authors: Ruiwu Liu; Jan Marik; Kit S Lam
Journal: J Am Chem Soc Date: 2002-07-03 Impact factor: 15.419

8. An improved method for rapid sequencing of support-bound peptides by partial edman degradation and mass spectrometry.

Authors: Michael C Sweeney; Dehua Pei
Journal: J Comb Chem Date: 2003 May-Jun

Review 9. Enzymology and biology of CaaX protein prenylation.

Authors: H W Fu; P J Casey
Journal: Recent Prog Horm Res Date: 1999

10. Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis.

Authors: Seiji Takashima; Masafumi Kitakaze; Masanori Asakura; Hiroshi Asanuma; Shoji Sanada; Fumi Tashiro; Hitoshi Niwa; Jun-ichi Miyazaki Ji; Seiichi Hirota; Yukihiko Kitamura; Takashi Kitsukawa; Hajime Fujisawa; Michael Klagsbrun; Masatsugu Hori
Journal: Proc Natl Acad Sci U S A Date: 2002-03-12 Impact factor: 11.205

3 in total