Literature DB >> 28238171

Using a relative health indicator (RHI) metric to estimate health risk reductions in drinking water.

Katherine A Alfredo1, Chad Seidel2,3, Amlan Ghosh4, J Alan Roberson5.   

Abstract

When a new drinking water regulation is being developed, the USEPA conducts a health risk reduction and cost analysis to, in part, estimate quantifiable and non-quantifiable cost and benefits of the various regulatory alternatives. Numerous methodologies are available for cumulative risk assessment ranging from primarily qualitative to primarily quantitative. This research developed a summary metric of relative cumulative health impacts resulting from drinking water, the relative health indicator (RHI). An intermediate level of quantification and modeling was chosen, one which retains the concept of an aggregated metric of public health impact and hence allows for comparisons to be made across "cups of water," but avoids the need for development and use of complex models that are beyond the existing state of the science. Using the USEPA Six-Year Review data and available national occurrence surveys of drinking water contaminants, the metric is used to test risk reduction as it pertains to the implementation of the arsenic and uranium maximum contaminant levels and quantify "meaningful" risk reduction. Uranium represented the threshold risk reduction against which national non-compliance risk reduction was compared for arsenic, nitrate, and radium. Arsenic non-compliance is most significant and efforts focused on bringing those non-compliant utilities into compliance with the 10 μg/L maximum contaminant level would meet the threshold for meaningful risk reduction.

Entities:  

Keywords:  Drinking water; Health risk; Regulation; Regulatory determination; USEPA

Mesh:

Substances:

Year:  2017        PMID: 28238171     DOI: 10.1007/s10661-017-5815-8

Source DB:  PubMed          Journal:  Environ Monit Assess        ISSN: 0167-6369            Impact factor:   2.513


  6 in total

Review 1.  Assessing the risks of exposures to multiple chemicals with a common mechanism of toxicity: how to cumulate?

Authors:  C F Wilkinson; G R Christoph; E Julien; J M Kelley; J Kronenberg; J McCarthy; R Reiss
Journal:  Regul Toxicol Pharmacol       Date:  2000-02       Impact factor: 3.271

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Journal:  Mutat Res       Date:  1998-09       Impact factor: 2.433

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Authors:  M L Dourson; S P Felter; D Robinson
Journal:  Regul Toxicol Pharmacol       Date:  1996-10       Impact factor: 3.271

4.  Current and future risk assessment guidelines, policy, and methods development for chemical mixtures.

Authors:  L K Teuschler; R C Hertzberg
Journal:  Toxicology       Date:  1995-12-28       Impact factor: 4.221

5.  Cumulative Risk Assessment (CRA): transforming the way we assess health risks.

Authors:  Pamela R D Williams; G Scott Dotson; Andrew Maier
Journal:  Environ Sci Technol       Date:  2012-09-11       Impact factor: 9.028

Review 6.  Cumulative risk assessment: an overview of methodological approaches for evaluating combined health effects from exposure to multiple environmental stressors.

Authors:  Ken Sexton
Journal:  Int J Environ Res Public Health       Date:  2012-01-26       Impact factor: 3.390

  6 in total

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