Literature DB >> 28238055

The status of intensive care medicine research and a future agenda for very old patients in the ICU.

H Flaatten1,2, D W de Lange3, A Artigas4, D Bin5, R Moreno6, S Christensen7, G M Joynt8, Sean M Bagshaw9, C L Sprung10, D Benoit11, M Soares12, B Guidet13,14,15.   

Abstract

The "very old intensive care patients" (abbreviated to VOPs; greater than 80 years old) are probably the fastest expanding subgroup of all intensive care unit (ICU) patients. Up until recently most ICU physicians have been reluctant to admit these VOPs. The general consensus was that there was little survival to gain and the incremental life expectancy of ICU admission was considered too small. Several publications have questioned this belief, but others have confirmed the poor long-term mortality rates in VOPs. More appropriate triage (resource limitation enforced decisions), admission decisions based on shared decision-making and improved prediction models are also needed for this particular patient group. Here, an expert panel proposes a research agenda for VOPs for the coming years.

Entities:  

Keywords:  Elderly; Frailty; ICU; Mortality; Octogenarians; Severity of illness

Mesh:

Year:  2017        PMID: 28238055     DOI: 10.1007/s00134-017-4718-z

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN: 0342-4642            Impact factor:   17.440


  58 in total

1.  Long-term association between frailty and health-related quality of life among survivors of critical illness: a prospective multicenter cohort study.

Authors:  Sean M Bagshaw; H Thomas Stelfox; Jeffrey A Johnson; Robert C McDermid; Darryl B Rolfson; Ross T Tsuyuki; Quazi Ibrahim; Sumit R Majumdar
Journal:  Crit Care Med       Date:  2015-05       Impact factor: 7.598

2.  Mortality in elderly ICU patients: a cohort study.

Authors:  M S Nielsson; C F Christiansen; M B Johansen; B S Rasmussen; E Tønnesen; M Nørgaard
Journal:  Acta Anaesthesiol Scand       Date:  2013-10-13       Impact factor: 2.105

3.  Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.

Authors:  Kees J Kalisvaart; Jos F M de Jonghe; Marja J Bogaards; Ralph Vreeswijk; Toine C G Egberts; Bart J Burger; Piet Eikelenboom; Willem A van Gool
Journal:  J Am Geriatr Soc       Date:  2005-10       Impact factor: 5.562

4.  Risk of post-traumatic stress symptoms in family members of intensive care unit patients.

Authors:  Elie Azoulay; Frédéric Pochard; Nancy Kentish-Barnes; Sylvie Chevret; Jérôme Aboab; Christophe Adrie; Djilali Annane; Gérard Bleichner; Pierre Edouard Bollaert; Michael Darmon; Thomas Fassier; Richard Galliot; Maité Garrouste-Orgeas; Cyril Goulenok; Dany Goldgran-Toledano; Jan Hayon; Mercé Jourdain; Michel Kaidomar; Christian Laplace; Jérôme Larché; Jérôme Liotier; Laurent Papazian; Catherine Poisson; Jean Reignier; Fayçal Saidi; Benoît Schlemmer
Journal:  Am J Respir Crit Care Med       Date:  2005-01-21       Impact factor: 21.405

5.  Increased intensity of treatment and decreased mortality in elderly patients in an intensive care unit over a decade.

Authors:  Nicolas Lerolle; Ludovic Trinquart; Caroline Bornstain; Jean-Marc Tadié; Audrey Imbert; Jean-Luc Diehl; Jean-Yves Fagon; Emmanuel Guérot
Journal:  Crit Care Med       Date:  2010-01       Impact factor: 7.598

6.  Withholding or withdrawal of treatment under French rules: a study performed in 43 intensive care units.

Authors:  Olivier Lesieur; Maxime Leloup; Frédéric Gonzalez; Marie-France Mamzer
Journal:  Ann Intensive Care       Date:  2015-06-19       Impact factor: 6.925

7.  Postoperative admission to a dedicated geriatric unit decreases mortality in elderly patients with hip fracture.

Authors:  Jacques Boddaert; Judith Cohen-Bittan; Frédéric Khiami; Yannick Le Manach; Mathieu Raux; Jean-Yves Beinis; Marc Verny; Bruno Riou
Journal:  PLoS One       Date:  2014-01-15       Impact factor: 3.240

8.  Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study.

Authors:  Daniel H J Davis; Graciela Muniz Terrera; Hannah Keage; Terhi Rahkonen; Minna Oinas; Fiona E Matthews; Colm Cunningham; Tuomo Polvikoski; Raimo Sulkava; Alasdair M J MacLullich; Carol Brayne
Journal:  Brain       Date:  2012-08-09       Impact factor: 13.501

9.  Trends in severity of illness on ICU admission and mortality among the elderly.

Authors:  Lior Fuchs; Victor Novack; Stuart McLennan; Leo Anthony Celi; Yael Baumfeld; Shinhyuk Park; Michael D Howell; Daniel S Talmor
Journal:  PLoS One       Date:  2014-04-03       Impact factor: 3.240

10.  Long-term outcome of delirium during intensive care unit stay in survivors of critical illness: a prospective cohort study.

Authors:  Annemiek E Wolters; Diederik van Dijk; Wietze Pasma; Olaf L Cremer; Marjolein F Looije; Dylan W de Lange; Dieuwke S Veldhuijzen; Arjen J C Slooter
Journal:  Crit Care       Date:  2014-06-18       Impact factor: 9.097

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  55 in total

1.  Focus on infection and sepsis 2017.

Authors:  Ignacio Martin-Loeches; Jose Garnacho-Montero; Saad Nseir
Journal:  Intensive Care Med       Date:  2017-04-04       Impact factor: 17.440

2.  Healthcare-related costs in very elderly intensive care patients.

Authors:  L E M Haas; Ilse van Beusekom; Diederik van Dijk; Marije E Hamaker; Ferishta Bakhshi-Raiez; Dylan W de Lange; Nicolette F de Keizer
Journal:  Intensive Care Med       Date:  2018-09-25       Impact factor: 17.440

3.  Frailty as a Prognostic Indicator in Intensive Care.

Authors:  Christian Jung; Raphael Romano Bruno; Bernhard Wernly; Georg Wolff; Michael Beil; Malte Kelm
Journal:  Dtsch Arztebl Int       Date:  2020-10-02       Impact factor: 5.594

Review 4.  Bloodstream infections in the elderly: what is the real goal?

Authors:  Yaara Leibovici-Weissman; Noam Tau; Dafna Yahav
Journal:  Aging Clin Exp Res       Date:  2019-09-05       Impact factor: 3.636

5.  Should this elderly patient be admitted to the ICU?

Authors:  Bertrand Guidet; Dylan W de Lange; Hans Flaatten
Journal:  Intensive Care Med       Date:  2018-01-22       Impact factor: 17.440

6.  The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years).

Authors:  Hans Flaatten; Dylan W De Lange; Alessandro Morandi; Finn H Andersen; Antonio Artigas; Guido Bertolini; Ariane Boumendil; Maurizio Cecconi; Steffen Christensen; Loredana Faraldi; Jesper Fjølner; Christian Jung; Brian Marsh; Rui Moreno; Sandra Oeyen; Christina Agwald Öhman; Bernardo Bollen Pinto; Ivo W Soliman; Wojciech Szczeklik; Andreas Valentin; Ximena Watson; Tilemachos Zaferidis; Bertrand Guidet
Journal:  Intensive Care Med       Date:  2017-09-21       Impact factor: 17.440

7.  Focus on ethics and palliative care in the intensive care unit.

Authors:  Katherine R Courtright; Dominique D Benoit; J Randall Curtis
Journal:  Intensive Care Med       Date:  2019-03-25       Impact factor: 17.440

8.  Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit.

Authors:  Bertrand Guidet; Hans Flaatten; Ariane Boumendil; Alessandro Morandi; Finn H Andersen; Antonio Artigas; Guido Bertolini; Maurizio Cecconi; Steffen Christensen; Loredana Faraldi; Jesper Fjølner; Christian Jung; Brian Marsh; Rui Moreno; Sandra Oeyen; Christina Agwald Öhman; Bernardo Bollen Pinto; Ivo W Soliman; Wojciech Szczeklik; Andreas Valentin; Ximena Watson; Tilemachos Zafeiridis; Dylan W De Lange
Journal:  Intensive Care Med       Date:  2018-05-17       Impact factor: 17.440

9.  Effect of Systematic Intensive Care Unit Triage on Long-term Mortality Among Critically Ill Elderly Patients in France: A Randomized Clinical Trial.

Authors:  Bertrand Guidet; Guillaume Leblanc; Tabassome Simon; Maguy Woimant; Jean-Pierre Quenot; Olivier Ganansia; Maxime Maignan; Youri Yordanov; Samuel Delerme; Benoit Doumenc; Muriel Fartoukh; Pierre Charestan; Pauline Trognon; Bertrand Galichon; Nicolas Javaud; Anabela Patzak; Maïté Garrouste-Orgeas; Caroline Thomas; Sylvie Azerad; Dominique Pateron; Ariane Boumendil
Journal:  JAMA       Date:  2017-10-17       Impact factor: 56.272

10.  Premorbid functional status as a predictor of 1-year mortality and functional status in intensive care patients aged 80 years or older.

Authors:  Laura Pietiläinen; Johanna Hästbacka; Minna Bäcklund; Ilkka Parviainen; Ville Pettilä; Matti Reinikainen
Journal:  Intensive Care Med       Date:  2018-07-02       Impact factor: 17.440

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